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THE
CANADIAN
FORMULARY
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UNOFFICIAL PREPARATIONS
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Approved «nd Adopted by
THE CANADIAN PHARMACEUTICAL ASSOCIATION
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The Ontario GolJege of Pharmacy
TORONTO. ONT.
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Digitized by the Internet Archive
in 2010 with funding from
University of Toronto
http://www.archive.org/details/canadianformular1921onta
THE
Canadian Formulary
OP
UNOFFICIAL PREPARATIONS
(5tli Edition)
BY AUTHORITY OF
THE ONTARIO COLLEGE OF PHARMACY
PRICE 75 CENTS
Published by
THE ONTARIO COLLEGE OF PHARMACY
TORONTO, ONTARIO.
1921
'31
PREFACE TO FOURTH EDITION
np HE Committee on Education and Research of the Ontario College of
Pharmacy, in issuing a reprint of the Canadian Formulary, desires
to express its gratification on the extended appreciation accorded to the
formulary, as attested by the need for another provision to meet the
steady demand for it. The present issue boasts of but few additions to
the formulas presented in the last edition. This may properly be ac-
counted for in great part by the thorough manner in which the former
editor, Mr. John Hargreaves, achieved the work entrusted to him. The
committee deems it fitting to record its appreciation of the praiseworthy
service rendered to his brother pharmacists, and to the cause of ethical
pharmacy by Mr. Hargreaves. It would like to hope that his example
might be imitated by every member of the pharmaceutical profession by
the contribution of such formulas as may be found useful or necessary.
Only in this way can the purpose of the Formulary be promoted and its
practical utility enhanced. Let the Committee have the benefit of any
formulas deemed worthy of a place. Also let the Committee have the
benefit of any criticism of the Formulary you believe necessary for its
betterment.
Toronto, July 1st, 1915.
I
PREFACE
(Reproduced from the 3rd Edition)
X this third edition of the Canadian Formulary the committee has made
- a few necessary alterations in some of the formulas published In 1908.
A number of new preparations have been added and it is hoped that these
will be of service to the medical and pharmaceutical professions of the
Dominion.
It is gratifying to the committee to find that in many parts of Canada,
the work is highly appreciated by the medical profession, and this inter-
est would be largely increased, if the pharmacists and physicians in each
locality would consult together, and offer suggestions and additional
formulas according to the requirements of the various localities.
As explained in previous editons, the object of the committee has been
to provide a definite standard, for the manufacture of certain pharmaceu-
tical preparations, which are frequently required by the medical profes-
sion, but for which there was no uniform or authorized standard up to
the time this work was undertaken, and much confusion and inconven-
ience was caused by the lack of uniformity in the products of various
houses marketing preparations known by the same trade names.
It is only by the active support and co-operation of the medical pro-
fession that we can hope to gain the full benefits of the work undertaken.
It is, therefore, desirable that the physicians of Canada be made acquaint-
ed with the existence, contents and objects of this publication, and if this
is dpne by the pharmacists in each locality, we believe that physicians
will gladly use and prescribe the "C. F." preparations, instead of desig-
nating any particular manufacturer's product.
The committee invite correspondence from all parts of the Dominion
on matters pertaining to the Formulary, and will gratefully receive any
suggestions as to improvements, or additional formulas for the next edi-
tion. All such formulas will be carefully considered and practically tested.
Careful consideration will also be given by the committee to any re-
quests for additional formulas to meet the requirements of the physicians
of any particular locality.
It has been the desire of the committee to make this little work of
practical value to the pharmacist, who has been obliged to keep in stock a
large variety of "brands," all known by practically the same trade name,
but made of varying strengths, and exploited by different manufacturers,
and greatly to the disadvantage and bewilderment of both physician and
pharmacist.
The preparations of the "C. F." were all thoroughly tested before
they were adopted, and any one of them can be readily prepared by any
pharmacist on his own premises, and we feel that it will be to the advan-
tage of physicians, pharmacists and patients, if the pharmacists of the
Dominion will interest themselves in calling the attention of their friends
in the medical profession to the advantages of specifying "C. F." prepara-
tions in their prescriptions, and using them as frequently as possible.
PREFACE
(Reproduced from the 2nd Edition)
THIS second edition of the Canadian Formulary is published under the
authority of the Ontario College of Pharmacy ,by committees from
the Colleges of Pharmacy, of the Provinces of Ontario and Quebec, ap-
pointed for the purpose of investigating and approving of formulas be-
lieved to be appropriate and suitable for the purpose and object for which
the publication is authorized.
Recognition of certain formulas bearing a semi-official title prepared
according to the formulas prevailing in localities, has demonstrated the
necessity for the adoption of some uniform system of authoritative form-
ulas, whereby the physician can intelligently prescribe and the pharma-
cist dispense, and the result expected and obtained be unifoi'm and iden-
tical throughout the whole of the Dominion of Canada. This was the
desire and intention of the Council of the Ontario College of Pharmacy,
when the work was inaugurated, with the full knowledge and belief, that
only by and with the general co-operation and support of the pharmacists
of the entire Dominion could success be achieved. Recent developments
point to much encouragement for a wider co-operation and assistance
from the pharmacists, from which we feel justified in the conclusion that
most valuable and material benefits will accrue.
The establishment of uniform and authoritative standards for medi-
cinal articles to meet the demands of the medical and pharmaceutical
professions for preparations brought to the attention of the prescriber,
under various and fanciful coined names, with very extravagant claims
for medicinal value indicated as possessed only by the one special prep-
aration and marketed at fanciful trade prices, is essentially a step in the
interests of the public and the professions.
The best means of introducing the peparations, or the most success-
ful method of obtaining due recognition of them, should be
through personal introduction to the physician by the pharmacist. If the
pharmacist will carefully examine these formulas, it is believed,
that many of them will be found particularly applicable to the require-
ments of his locality and can be readily prepared by any qualified phar-
maceutical chemist, and with an intelligent understanding of the medicinal
properties of the preparation, as well as a knowledge of any extravagant
claims for competitive proprietary articles, the efficient pharmacist
should be able to impress the physician and induce him to test the relia-
bility of the preparations presented.
Attention is particularly directed to the fact that many formulas aro
included in the book for the express purpose of enabling the pharmacist
to supply the popular demand for preparations on the market for which
the formulas published will produce an article of like properties, and
that in some cases the formula is not to be considered or recommended
as a truly scientific pharmaceutical exhibit of the ingredients contained
in the preparation, (as shown in Formulas numbered 33 and 35).
The formulas are largely selected and compiled from a careful sur-
vey and investigation of many recognized authorities, with the intention
on the part of the committee of allowing due credit in each case to the
source from which it is obtained. Valuable assistance was given the
work by many pharmacists in Ontario and Quebec, also by Prof. Chas. F.
Heebner, Dean of the Ontario College of Pharmacy; J. E .Morrison, Mont-
real College of Pharmacy, and Fred W. Flett, Toronto, who are worthy of
especial mention, and to whom a large shar^ of credit is due. Criticisms
and suggestions on all formulas will be cheerfully received by the com-
mittees and recommendations for new formulas eligible for inclusion
in subsequent editions, will materially advance the scope and usefulness
of the work.
Both Imperial and Metric weights and measures are given through-
out the Formulary. It has been somewhat diflBicult, in the course of a
single paragraph embodying formulas involving definite quantities of
materials, to give precise directions for their employment in two different
systems of weights and measures, hence those who use the Formulary are
requested to avoid the assumption that Imperial and Metric quantities
thus placed in juxtaposition are necessarily equivalent to one another.
The intention has been to furnish formulas that will yield liquid pro-
ducts measuring twenty fluidounces (or a convenient mutiple of that vol-
ume) or one thousand cubic centimeters. Except for wholly insignifi-
cant fractional differences, a preparation made according to either sys-
tem will contain the same proportions of ingredients; but the two sys-
tems cannot both be used in the same operation, and are, therefore, not
interchangeable.
The term "Diluted Alcohol" which occurs throughout the text, refers
to a mixture of equal volumes of Commercial Alcohol (95%) and Distilled
Water.
THE CANADIAN FORMULABY 3
1. ACIDUM HYPOPHOSPHOROSUM
Hypophosphorus Acid
(N.F. 1906)
Hypophosphite of Potassium 483 parts
Tartaric Acid 682 parts
Distilled Water 500 parts
Diluted Alcohol ("45% Alcohol") 1000 pirts
Dissolve the potassium hypophosphite in 500 parts of dis-
tilled water previously warmed, and the tartaric acid in 1000
parts of diluted alcohol. Mix the solutions in a flask of sufficient
capacity to permit agitation, cork and shake well and set the
flask in a bath of ice water for 12 hours. Then carefully pour
the mixture into a funnel, the neck of which has been closed with
a pledget of cotton, and when all the liquid has been drained off,
rinse the flask, and wash the crystalline precipitate in the funnel
with small portions of cold diluted alcohol until the washings no
longer respond to the tests for hypophosphorus acid (black pre-
:ipitate with silver nitrate test solution or white precipitate with
mercuric chloride test solution). Mix the original filtrate and
the washings and evaporate the whole on a water-bath at the
temperature not exceeding 140° F. (60° C.) until all the alcohol
has been dissipated. Allow the liquid to cool and add sufficient
distilled water to bring the weight up to 1000 parts. Preserve
the product in well stoppered bottles.
Note.— This should contain 30 per cent, of hydrogen hypophosphite.
2. ALCOHOL DEODORATUM
Deodorized Alcohol
(N.F. 1896)
Powdered Quicklime 300 grains 20.0 Gm.
Powdered Alum 150 grains 10.0 Gm.
Spirit of Nitrous Ether 1% fluidrachm 4.5 mils
Alcohol (95 per cent.) 160 fluidounces 5000 mils
Mix the lime and alum intimately by trituration ; add to the
alcohol and shake well, then add the spirit of nitrous ether, set
aside for seven days and filter through powdered animal charcoal.
3. AQUA OLEI ROS/E
Rose Water
Oil of Rose 1.0 mil
Calcium Phosphate or Purified Talcum. . 2.0 Gm.
Distilled Water 500.0 mils
Triturate the oil of rose with the phosphate of calcium (or
purified talcum), gradually add the distilled water, with con-
tinued trituration, and filter.
4 THE CANADIAN FORMULARY
Note.— The following medicated waters may be made in the same
manner as rose water, and used in the place of the corresponding Aquae
of the text of the B. P.—
Aqua Olei Anethi.
Aqua Olei Anisi.
Aqua Olei Carui.
Aqua Olei Cinnamomi.
Aqua Olei Foeniculi.
Acqa Olei Menthae Viridis.
Aqua Olei Menthae Piperitse.
Aqua Olei Pimentse.
4. CAPSUL>E APIOL ET ERGOTINl
Capsules of Apiol and Ergotin
Each capstile to contain apiol five minims (3 decimils) and
ergotin two grains (0.13 Gm.)
5. CAPSUL^E COLCHICIN/E ET METHYL SALICYLATIS
Capsules of Salicylates of Colchicine and Methyl
Colchicine Salicylate 1 grain .065 Gm.
Methyl Salicylate 1250 minims 74.0 mils
iPissolve and fill into 250 capsules.
Each capsule contains colchicine l-250th grain (0.00025 Gm.)
and methyl salicylate five minims (3 decimils). Average dose--
one capsule.
6. CATAPLASMA KAOLINI
Cataplasm of Kaolin
(U.S.P. 1905)
Kaolin, in very fine powder 11^ ounces 577.0 Gm.
Boric Acid, in very fine powder 395 grains 45.0 Gm.
Thymol 5 grains 0.5 Gm.
Methyl salicylate (Synthetic Oil of
Wintergreen) 20 grains 2.0 Gm.
Oil of Peppermint 5 grains 0.5 Gm.
Glycerin 7^ fiuidounces 375.0 Gm.
Heat the kaolin in a suitable vessel at 230° F. (110° C.) with
occasional stirring, for one hour. Heat the glycerin to 212° F.
(100° C.) and while yet warm dissolve in it the boric acid and in-
corporate the hot kaolin with this liquid. Dissolve the thymol
in the methyl salicylate and the oil of peppermint, and mix with
the above to form a homogeneous mass. The product should be
kept in air-tight containers.
THE CANADIAN' FORMULARY 5
7. CERATUM PARAFFINI
Cerate of Paraffin
Cold Cream
Liquid Parafin 16 fluidounces 160.0 mils
White Beeswax 4 ounces 40.0 Gm.
Spermaceti 1 oimce 10.0 Gm.
Borax 30 grains 0.6 mils
Oil of Rose 10 minims 0.2 mils
Distilled Water 8 fluidounces 80.0 mils
Dissolve the borax in the distilled water; melt the white
beeswax and spermaceti with the liquid paraffin at a gentle heat ;
pour the mixture into a warmed mortar and add while yet hot the
borax solution (previously warmed) with constant trituration,
and finally the oil of rose, and continue the trituration until cold.
In hot weather the quantity of white beeswax may be in-
creased to 5y^ ounces (53 Gm.) and the spermaceti to 2 ounces
(20 Gm.).
8. CHLORAL CAMPHORATUM
Camphorated Chloral
Chloral 2 ounces 50.00 Gm.
Camphor 2 ounces 50.00 Gm.
Mix them by agitation in a bottle, or by trituration in a warm
mortar until liquefied and combined.
9. CHLOROFORMUM CAMPHORATUM
Camphorated Chloroform
Camphor 2 ounces 200.0 Gm.
Chloroform 1 fluidounce 100.0 mils
9a. COLLODIUM BELLADONN/C
B.P.C.
Belladonna Collodion
Emplastrum Belladonnae Fluidum
Liquid Extract of Belladonna ........ 20 fluidounces 50.0 mils
Canada Balsam 768 grains 4.0 Gm.
Castor Oil 384 minims 2.0 mils
Camphor 288 grains 1.5 Gm.
Pyroxylin 1 ounce 2.5 Gm.
Ether, sufficient to make 40 fluidounces 100 mils
Mix the extract of belladonna, Canada balsam, castor oil and
16 fluidounces (400 mils) of the ether. Shake well; allow to
stand twelve hours, and decant ; then filter and dissolve the
camphor and pyroxylin in the mixture and add sufficient ether to
make 40 fluidounces (1(XX) mils).
6 THE CANADIAN FORMULARY
10. COLLODIUM lODOFORMATUM
Iodoform Collodion
(N.F. 1906)
Iodoform, in fine powder 5 parts
Flexible Collodion 95 parts
Dissolve the iodoform in the flexible collodion contained in
a dry bottle, by agitation.
Note. — This preparation should be made extemporaneously.
11. ELIXIR ACETANILIDI COMPOSITUM
Compound Elixir of Acetanilide
Acetanilide 400 grains 22.75 Gm.
Phenacetin 320 grains 18.3 Gm.
Sodium Bromide 3 ounces 288 grains 91.5 Gm.
CaflFeine Citrate 160 grains 9.15 Gm.
Tartaric Acid 80 grains 4.58 Gm.
Sodium Bicarbonate 1 ounce 32 grains 27.5 Gm.
Aromatic Elixir, sufficient to make. . 40 fluidounces 1000 mils
Mix the phenacetin, acetanilide. tartaric acid and sodium
bicarbonate and dissolve in 20 fluidounces (500 mils) of aro-
msllic elixir. To this solution add the sodium bromide and caf-
feine citrate, then add sufficient aromatic elixir to make 40 fluid-
Dunces ( 1000 mils) and filter if necessary.
12. ELIXIR ADJUVANS
Adjuvant Elixir
(U.S. P. 1905)
Fluid Extract of Glycyrrhiza 2^/^ fluidounces 120 mils
Aromatic Elixir 17^ fluidounces 880 mils
Mix and filter if necessary.
13. ELIXIR AMMONII BROMIDI
Elixir of Ammonium Bromide
Ammonium Bromide 1600 grains 91.5 Gm.
Citric Acid 70 grains 4.0 Gm.
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
Dissolve the arhmonium bromide and citric acid in about 20
fluidounces (500 mils) of aromatic elixir, by agitation. Then
add enough aromatic elixir to make 40 fluidounces (1000 mils)
and filter if necessary.
Each fluidrachm contains 5 grains (0.32 Gm.) of ammonium
bromide.
THE CANADIAN FORMULARY 7
14. ELIXIR ANISI
Elixir of Anise
Aniseed Cordial
Anethol 65 minims. 3.5 mils
Oil of Fennel 10 minims. 0.5 mils
Spirit of Bitter Almond 4 flviidrachms 12.0 mils
Deodorized Alcohol 9^^ fluidounces 240.0 mils
Syrup 25 fluidounces 625.0 mils
Purified Talc 360 grains 20.0 Gm.
Distilled Water, sufficient to make . . 40 fluidounces 1000 mils
Mix the anethol, the oil and the spirit of bitter almond with
the deodorized alcohol, add the syrup and sufficient distilled
water to make 40 fluidounces (1000 mils). Then mix it inti-
mately with the purified talc and set the mixture aside for 12
hours. Then cool it to about 60° F. (15° C.) and filter, returning
the first portion of the filtrate until it passes perfectly clear.
15. ELIXIR AROMATICUM
Aromatic Elixir
Compound Spirit of Orange 230 minims. 12.0 mils
Syrup 14 fluidounces 350.0 mils
Purified Talc 360 grains 20.0 Gm.
Deodorized Alcohol and Distilled Water,
a sufficient quantity of each to make 40 fluidounces 1000 mils
To the compound spirit of orange add enough alcohol to
make 10 fluidounces (250 mils). To this solution add the syrup
in portions, shaking after each addition, and afterwards add in
the same manner distilled water 15 fluidounces (375 mils). In-
timately mix the talc with the liquid and filter through a wetted
filter returning the first portions of the filtrate, until a transparent
liquid is obtained. W^ash the filter with a mixture of alcohol
one volume and distilled water three volumes until the product
measures 40 fluidounces (1000 mils).
16. ELIXIR AURANTII
Elixir of Orange
Simple Elixir
Spirit of Orange 4 fluidounces 40.0 mils
Deodorized Alcohol 25 fluidounces 250.0 mils
Simple Syrup 40 fluidounces 400.0 mils
Purified Talcum 380 grains 20.0 Gm.
Distilled Water 31 fluidounces 310.0 mils
Mix the several ingredients in the order named ; shake occa-
sionally and filter, returning the first portion of the filtrate until
it passes perfectly clear.
8 THE CANADIAN FORMULARY
17. ELIXIR QUININE BROMIDORUM
Elixir of Five Bromides
Potassium Bromide 1600 grains 91.50 Gm.
Sodium Bromide 1600 grains 91.50 Gm.
Ammonium Bromide 480 grains 55.00 Gm.
Calcium Bromide 480 grains 27.45 Gm.
Lithium Bromide 160 grains 9.15 Gm.
Tincture of Cannabis Indica 2 fluidounces 50.00 mils
Aromatic Elixir, sufficient to make . 40 fluidounces 1000 mils
Dissolve the bromides in the aromatic elixir, add the tincture
of cannabis indica and filter, if necessary.
18. ELIXIR BUCHU ET HYOSCYAMI COMPOSITUM
Compound Elixir of Buchu and Hyoscyamus
Fluid Extract Buchu 3 fluidounces 75.0 mils
Fluid Extract Uva Ursi V/z fluidounces 37.5 mils
Fluid Extract Pareira 1^ fluidounces 37.5 mils
Fluid Extract Hyoscyamus 1^^ fluidounces 37.5 mils
Fluid Extract Hops 1^2 fluidounces 37.5 mils
Potassium Acetate 2 ounces 291 grains 68.2 Gm.
Spirit of Nitrous Ether 4^^ fluidounces 112.5 mils
Aromatic Elixir, sufficient to make. . . 40 fluidounces 1000 mils
0j\lix and set aside for two days. Filter, if necessary.
19. ELIXIR CALCII ET SODII GLYCEROPHOSPHATIS
Elixir of Glycerophosphate of Calcium and Sodium
Calcium Glycerophosphate 320 grains 18.30 Gra.
Sodium Glycerophosphate, 75% . . .213 grains 12.20 Gm.
Gluside 5 grains 0.286 Gm.
Concentrated Phosphoric Acid ....150 grains 8.58 Gm.
Tinct. of Fresh Sweet-Orange Peel 1^ fluidounces 31.25 mils
Glycerin 7^/2 fluidounces 187.50 mils
Sherry Wine 10 fluidounces 250.0 mils
Distilled Water, sufficient to make 40 fluidounces 1000 mils
Dissolve the glycerophosphates of calcium and sodium in ten
fluidounces (250 mils) of distilled water with which the concen-
trated phosphoric acid has been previously mixed. Then add the
glycerin, sherry and the gluside dissolved in the tincture of
orange and enough distilled water to make the finished elixir
measure 40 fluidounces (1000 mils.) Filter through paper
sprinkled with talcum.
Note. — Each fluidrachin contains glycero-phosphate of calcium, 1
grain (0.065 Gm.) and glycerophosphate of sodium, y^ grain (.0325 Gm.).
Inasmuch as the glycerophosphates of commerce are of varied
strengths, the quantity will have to be regulated according to the strength
of the article used.
THE CANADIAN FORMULARY 9
19a. ELIXIR CALISAYyC PHOSPHATUM
Phosphated Elixir of Caiisaya
Quinine Sulphate 40 grains 2.0 Gm.
Cinchonine Sulphate 20 grains 1.0 Gm.
Cinchonidine Sulphate , . . 20 grains 1.0 Gm.
Tincture of Cudbear 2 fluidounces 50.0 mils
Solution of Ammonia, q. s.
Dilute Phosphoric Acid, q. s.
Elixir of Orange, sufficient to make . . .40 fluidounces 1000 mils
Dissolve the salts in 36 fluidounces (900 mils) of elixir of
orange, add solution of ammonia to slight excess and dilute
phosphoric acid to excess. Then add the tincture of cudbear and
sufficient elixir of orange to make 40 fluidounces, (1000 mils).
19b. ELIXIR CALISAY/e ET PHOSPHATUM
Elixir Caiisaya and Phosphates
Elixir of Caiisaya, Phosphated 5 fluidounces 125 mils
Compound Syrup of Phosphates .... 5 fluidounces 125 mils
Simple Syrup 27^ fluidounces 700 mils
Oil of Bitter Almonds 5 drops 0.52 mils
Distilled Water, sufficient to make . . .40 fluidounces 1000 mils
Mix.
20. ELIXIR CINCHON>e
Elixir of Cinchona. Elixir of Caiisaya
(Elixir of Cinchona from "Alkaloids")
Compound Elixir of Quinine
(N.F. 1906)
Quinine Sulphate 30 grains 2.0 Gm.
Cinchonidine Sulphate 15 grains 1.0 Gm.
Cinchonine Sulphate 15 grains 1.0 Gm.
Compound Tincture of Cudbear 1^ fluidounces 50.0 mils
Purified Talc ,320 grains 20.0 Gm.
Aromatic Elixir, sufficient to make . . 32 fluidounces 1000 mils
Dissolve the alkaloid salts in 30 fluidounces (900 mils) of
aromatic elixir ; add the compound tincture of cudbear and suffi-
cient aromatic elixir to make 32 fluidounces (1000 mils) and
triturate the purified talc with the mixture. Allow the mix-
ture to stand several hours, if convenient, occasionally shaking,
then filter, returning the first portions until the filtrate passes
perfectly clear.
Note. — Each fluidounce contains of quinine sulphate about 1 grain
(0.065 Gm.) and % grain (0.0325 Gm.) each of cinchonidine and cincho-
nine sulphates.
10 THE CANADIAN FORMULARY
21. ELIXIR CINCHON>E ET FERRI
Elixir of Cinchona and Iron
Ferrated Elixir of Cinchona
(N.F. 1906)
Soluble Ferric Phosphate 640 grains 36.6 mils
Water (boiling) 5 fluidounces 125.0 mils
Elixir of Cinchona, sufficient to make 40 fluidounces 1000 mils
Dissolve the soluble ferric phosphate in the boiling water,
then add elixir of cinchona sufficient to make 40 fluidounces
(1000 mils).
22. ELIXIR DIGITALINI COMPOSITUM
Compound Elixir of Digitalin
Digitalin (amorphous) 1^ grains 171 milligrams
Solution of Trinitrin, B. P 3 fluidrachms 18.65 mils
Solution of Trinitrin 3 fluidrachms 18.65 mils
Aromatic Elixir, q. s. ft 20 fluidounces 5(X) mils
Triturate the amorphous digitalin with a portion of the elixir
until a solution results. Then add to the remainder of the aro-
matic elixir the strychnine, trinitrin and digitalin solutions, in the
order mentioned, mixing thoroughly after each addition.
Note. — Each fluidrachm of this elixir contains approximately 1-lOOth
grain (0.6 milligrams) each of digitalin and trinitrin, and l-50th grain (1.25
milligrams) of strychnine hydrochloride.
Only amorphous digitalin should be used in making this preparation,
as the crystaline variety is believed to be five times stronger.
23. ELIXIR EUPHORBI/t COMPOSITUM
Compound Elixir of Euphorbia
(Anti-Asthmatic Elixir)
Sodium Iodide 640 grains 36.6 Gm.
Sodium Bromide 640 grains 36.6 Gm.
Fluid Extract of Euphorbia 2 fluidounces 50.0 mils
Tincture of Lobelia 1^4 fluidounces 31.5 mils
Solution of Trinitrin, B. P 3 fluidrachms 9.0 mils
Aromatic Elixir, sufficient to make ... 40 fluidounces ICXX) mils
Dissolve the sodium iodide and bromide in 20 fluidounces
(500 mils) of aromatic elixir, add the remaining ingredients, and,
lastly, sufficient aromatic elixir to make 40 fluidounces (1000
mils. Filter, if necessary.
THE CANADIAN FORMULARY 11
24. ELIXIR FERRI PYROPHOSPHATIS CUM QUININA ET
STRYCHNINA
Elixir of Pyrophosphate of Iron with Quinine and Strychnine
Quinine Sulphate 160 grains 9.0 Gm.
Sodium Citrate 150 grains 8.5 Gm.
Solution of Strychnine. B.P 500 minims 26.0 mils
Iron Pyrophosphate, soluble 600 grains 34.0 Gm.
Alcohol (95%) 5 fluidounces 125.0 mils
Glycerin 6 fluidounces 150.0 mils
Distilled Water 2 fluidounces 50.0 mils
Simple Elixir, sufficient to make .... 40 fluidounces 1000 mils
Dissolve the quinine in the alcohol and 6 fluidounces (150
mils) of simple elixir, using gentle heat if necessary, and add the
solution of strychnine. Dissolve the pyrophosphate of iron in
the water previously warmed, and 2 fluidounces (50 mils) of
simple elixir and add to it the solution of quinine and strych-
nine. Dissolve the sodium citrate in the glycerin ; mix the solu-
tions and add sufficient simple elixir to make 40 fluidounces
(1000 mils).
25. ELIXIR FERRI, QUININ>E ET STRYCHNIN/C
Elixir of Iron, Quinine and Strychnine
(N.F. 1906)
Tincture of Ferric Citro-Chloride . . 5 fluidounces 125.00 mils
Quinine Hydrochloride 156 grains 8.75 mils
Strychnine Sulphate 3% grains 0.175 Gm.
Alcohol (95%) 1 fluidounce 25.00 mils
Aromatic Elixir, sufficient to make . 40 fluidounces 1000 mils
Dissolve the alkaloidal salts in 32 fluidounces (750 mils) of
the elixir, then add the tincture and alcohol, and finally enough
aromatic elixir to make 40 fluidounces (1000 mils). Filter, if
necessary.
Each fluidrachm contains 1/100 grain (0.6 milligram) of
strychnine sulphate.
26. ELIXIR FORMINI
Elixir of Formin
Elixir Hexamethythlene-tetramine
Formin , . .600 grains 34.125 Gm.
Tincture of Cudbear 5 fluidrachms 15.0 mils
Aromatic Elixir, sufficient to make . 40 fluidounces 1000 mils
Dissolve the formin in the elixir, add the tincture of cudbear
and filter if necessary.
12 THE CANADIAN FORMULARY
27. ELIXIR GLYCYRRHIZ/C
Elixir of Glycyrrhiza
Elixir of Licorice
(N.F. 1906)
Fluid Extract of Licorice 5 fluidounces 125 mils
Aromatic Elixir 35 fluidounces 825 mils
Filter, if necessary.
28. ELIXIR GLYCEROPHOSPHATUM COMPOSITUM
Compound Elixir of Glycerophosphates
Calcium Glycerophosphate 160 grains 9.2 Gm.
*Sodium Glycerophosphate (75%) . .212 grains 9.2 Gm.
Iron Glycerophosphate (Scale) .... 80 grains 4.6 Gm.
♦Potassium Glycerophosphate (75%) 106 grains 4.6 Gm.
Citric Acid 76 grains 4.5 Gm.
Tincture of Sweet Orange Peel .... 50 fluidrachms 15.0 mils
Sodium Chloride 120 grains 7.0 Gm.
Gluside 4 grains 0.25 Gm.
Glvcerin 6 fluidounces 150.0 mils
Sherry Wine 10 fluidounces 250.0 mils
Distilled Water, sufficient to make . 40 fluidounces 1000 mils
Dissolve the calcium, sodium and potassium glycerophos-
phates and the citric acid in 12 fluidounces (300 mils) of warm
water and add the glycerin. Dissolve the iron glycerophosphate
m 2 fluidounces (50 mils) of hot water and add to the solution of
glycerophosphates and when cpol add the tincture of orange in
which the gluside has been previously dissolved, then the sherry
wine and sufficient water to make 40 fluidounces (1000 mils).
Filter through paper sprinkled with talc, returning the filtrate
until it passes perfectly clear.
Dose, 2 fluidrachms (8 mils).
♦Inasmuch as some glycerophosphates of commerce have varied
strengths, the quantity given above will have to be regulated according
to the strength of the glycerophosphate used.
29. ELIXIR GLYCEROPHOSPHATUM CUM QUININA ET .
STRYCHNINA
Elixir of Glycerophosphates with Quinine and Strychnine
Calcium Glycerophosphate 240 grains 13.8 Gm.
*Sodium Glycerophosphate (75%) . .212 grains 9.2 Gm.
♦Potassium Glycerophosphate (75%) 212 grains 9.2 Gm.
Magnesium Glycerophosphate 160 grains 9.2 Gm.
Iron Glycerophosphate (Scale) 80 grains 4.6 Gm.
Quinine Hydrochloride 20 grains 1.15 Gm.
Strychnine Hydrochloride 4 grains 0.25 Gm.
Citric Acid 60 grains 3.5 Gm.
Gluside 22 grains 1.25 Gm.
Tincture of Sweet Orange Peel 2 fluidounces 50.0 mils
Alcohol (95%) .■ 2 fluidounces 50.0 mils
Glycerin 10 fluidounces 250.0 mils
Distilled Water, sufficient to make.. 40. fluidounces 1000 mils
THE CANADIAN FORMULARY 13
Dissolve the glycerophosphates, the quinine, strychnine, and
the citric acid, in 20 fluidounces (500 mils) of warm water mixed
with the glycerin, and when cold add the tincture of orange peel
and the alcohol in which the gluside has been previously dis-
solved Filter through paper sprinkled with talc, and pass
sufficient distilled water through the filter to make 40 fluidounces
(1000 mils).
Each fluidrachm contains 1/80 grain strychnine hydrochloride.
Dose, 1 to 2 fluidrachms.
♦Inasmuch as some glycerophosphates of commerce have varied
strengths, the quantity given above will have to be regulated according
to the strength of the glycerophosphate used.
30. ELIXIR LITHII ET HYDRANGE/E
Elixir of Lithium and Hydrangea
Lithium Salicylate 600 grains 34.0 Gm.
Lithium Benzoate 300 grains 17.0 Gm.
Fluid Extract of Hydrangea 7y2 fluidounces 187.0 mils
Alcohol (95%) 7y2 fluidounces 187.0 mils
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
Dissolve the lithium salts in 25 fluidounces (625 mils) aro-
matic elixir, add the alcohol to the fluid extract of hydrangea and
mix all together. Let the mixture stand for twenty-four hours
and filter, if necessary.
31. ELIXIR LITHII SALICYLATIS
Elixir of Lithium Salicylate
(N.F. 1906)
Lithium Salicylate . 1600 grains 91.5 Gm.
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
Dissolve the Lithium Salicylate in sufficient aromatic elixir
to make 40 fluidounces (1000 mils) and filter.
Each fluidrachm contains 5 grains (0.325 Gm.) lithium sali-
cylate.
32. ELIXIR PAPAINI
Elixir of Papain
Papain 640 grains 30.5 Gm.
Diluted Hydrochloric Acid 150 minims. 8.0 mils
Distilled Water 6 fluidounces 150.0 mils
Glycerin 6 fluidounces 150.0 mils
Sherry Wine 6 fluidounces 150.0 mils
Gluside 20 grains 1.15 Gm..
Aromatic Elixir, sufficient to make . 40 fluidounces 1(X)0 mils
Macerate the papain in a mixture of the acid, glycerin and
water for four days, with occasional agitation. Dissolve the glu-
side in the wine and elixir, and mix with the papain mixture and
filter; then add aromatic elixir sufficient to make 40 fluidounces
(1000 mils).
14 THE CANADIAN FORMULARY
33. ELIXIR PEPSINI COMPOSITUM
Compound Elixir of Pepsin
Elixir Digestivum Compositum. Elixir of Digestive Ferments.
Elixir of Lacated Pepsin
(N.F. 1906)
Pepsin ( 1 in 3000) 175 grains 10.0 Gm.
Pancreatin 17^ grains 1.0 Gm.
Diastase 17^-^ grains 1.0 Gm.
Lactic Acid 15 minims 1.5 mils
Hydrochloric Acid 20 minims 2.0 mils
Glycerin 5 fluidounces 125.0 mils
Distilled Water 10 fluidounces 250.0 mils
Tincture of Cudbear 5 fluidounces 125.0 mils
Purified Talc 1 ounce 30.0 Gm.
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
Mix the acids with the glycerin and water, add the pepsin,
pancreatin and diastase to this mixture, and macerate with occa-
sional agitation until solution is apparently effected. Then add
the tincture of cudbear and enough aromatic elixir to make 40
fluidounces (1000 mils). Incorporate the purified talc thor-
oi^hly with the mixture and filter.
Note.— This preparation is included to enable the pharmacist to
meet a popular demand for an elixir of this name. It is not, however,
presented as a consistent scientific exhibit of the ingredients specified, it
being impossible to retain all three digestive ferments in active
condition in the same medium. The best commercial variety of diastase
capable of converting the largest amount of starch into dextrin and
maltose should be used.
34. ELIXIR PEPSINI COMPOSITUM CUM BISMUTHO
Compound Elixir of Pepsin with Bismuth
Elixir Lactated Pepsin with Bismuth
Pepsin (I in 3000) 175 grains 10.0 Gm.
Pancreatin 17i^ grains 1.0 Gm.
Diastase 17>^ grains 1.0 Gm.
Clycerin of Bismuth 5 fluidounces 125.0 mils
Lactic Acid 15 minims. 50.0 mils
Hydrochloric Acid .v... '.*... 20 minims. 1.0 mils
Glycerin 2 fluidounces 50.0 mils
Distilled Water 5 fluidounces 125.0 mils
Tincture of Cudbear 2 fluidounces 50.0 mils
Purified Talc 1 ounce 25.0 Gm.
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
THE CAXADIAX FORMULARY 15
Mix the acids with the glycerin and water, add the pepsin,
pancreatin and diastase to the mixture and macerate with fre-
quent agitation until solution is apparently effected. Then add
the glycerin of bismuth and tincture of cudbear and sufficient
aiomatic elixir to make 40 fluidounces (1000 milsj. Thoroughly
incorporate the purified talc and filter.
See note under formula No. 33.
35. ELIXIR PEPSINI COMPOSITUM CUM QUININA, FERRO ET
STRYCHNINA
Compound Elixir of Pepsin, with Quinine, Iron and Strychnine
Elixir of Lactated Pepsin, with Quinine, Iron and Strychnine.
Pepsin (1 in 3000) 175 grains 10.0 Gm.
Pancreatin 173^ grains 1.0 Gm.
Diastase 17^^ grains 1.0 Gm.
Quinine 120 grains 6.9 Gm.
Tincture of Citro-Chloride of Iron ... 2 fluidounces 50.0 mils
Purified Talc 1 ounce 25.0 Gm.
Solution of Strychnine (B.P.) 1 fluidounce 25.0 mils
Lactic Acid 15 minims. 150.0 mils
Hydrochloric Acid 20 minims. 1.0 mils
Glycerin 4 fluidounces 100.0 mils
Distilled Water 5 fluidounces 125.0 mils
Gluside 20 grains 0.2 Gm.
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
Mix the acids with the glycerin and water, add the pepsin,
pancreatin and diastase to the mixture and macerate with fre-
quent agitation until dissolved. Dissolve the gluside in 1 fluid-
ounce (25 mils) of distilled water. Dissolve the quinine in the
solution of iron, add the solution of strychnine, and 2 fluidounces
(50 mils) of aromatic elixir. Mix all together and lastly add
aromatic elixir sufficient ot make 40 fluidounces (1000 mils).
Thoroughly incorporate with the purified talc and filter.
Note.— Each fluidounce contains 3 grains (0.2 Gm.) of quinine and
one-eighth grain (0.008 Gm.) of strychnine. See. note under fromula
No. 33.
36. ELIXIR PEPSINI ET BISMUTHI
Elixir of Pepsin and Bismuth
Pepsin (1 in 3000) 160 grains 9.0 Gm.
Glycerin 4 fluidounces 100.0 mils
Glycerin of Bismuth 5 fluidounces 125.0 mils
Distilled Water 10 fluidounces 250.0 mils
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
16 THE CANADIAN FORMULARY
Dissolve the pepsin in the glycerin and distilled water, then
add the glycerin of bismuth and aromatic elixir. Mix thorough-,
ly and add' sufficient caramel to make a deep amber color.
Note. — Each fluidrachm contains V2 grain (0.0325 Gm.) of pepsin
and 2 grains (0.13 Gm.) of bismuth and ammonium citrate.
37, ELIXIR PEPSINI BISMUTHI ET STRYCHNIN/E
Elixir of Pepsin. Bismuth and Strychnine
Solution of Strychnine (B. P.) 176 minims. 18.3 mils
Elixir of Pepsin and Bismuth, sufficient
to make 20 fluidounces 1000 mils
Mix them, and if the elixir shows an acid reaction to blue
litmus, add solution of ammonia cautiously, until the reaction is
neutral.
Note. — Each fluidrachm contains 1/100 grain (0.6 milligrams)
strychnine hydrochloride.
38. ELIXIR POTASSII BROMIDI
Elixir of Potassium Bromide
Potassium Bromide 7 ounces 138 grains 183.0 Gm.
Distilled Water 7 fluidounces 175.0 mils
Solution of Carmine 35 minims. 2.0 mils
Elixir of Orange, sufficient to make . . 40 fluidounces 1000 mils
Dissolve the potassium bromide in the distilled water and
about 25 fluidounces (625 mils) of the elixir of orange by agita-
tion ; add the solution of carmine and sufficient elixir of orange
to make 40 fluidounces (1000 mils). Let stand a few hours and
filter.
Note. — Each fluidrachm contains 10 grains (0.65 Gm.) of potassium
bromide.
39. ELIXIR RHEI ET MAGNESII ACETATIS
Elixir of Rhubarb and Magnesium Acetate
(N.F. 1906)
Calcined Magnesia 355 grains 20.0 Gm.
Acetic Acid ^ a sufficient quantity
Fluid Extract of Rhubarb 5 fluidounces 125.0 mils
Aromatic Elixir sufficient to make ... 40 fluidounces 1000 mils
Dissolve the magnesia in 6 fluidounces (150 mils) of acetic
acid with the aid of a gentle heat, adding, if necessary, a little
more acetic acid, drop by drop, until the solution is neutral to test
paper. Then add the fluid extract and enough aromatic elixir to
make 40 fluidounces (1000 mils) and filter.
Each fluidrachm represents about 4 grains (0.25 Gm.) of
magnesium acetate and 7^^ grains (0.5 Gm.) of rhubarb.
THE CANADIAN FORMULARY 17
40. ELIXIR SERENO>e COMPOSITUM
Compound Elixir of Saw Palmetto
Fluid Extract of Saw Palmetto 2 fluiclounces 50.0 mils
Fluid Extract of Sandalwood 2 fluidounces 50.0 mils
Fluid Extract of Couch Grass 2 fluidounces 50.0 mils
Fluid Extract of Corn Silk 2 fluidounces 50.0 mils
Glycerin 2 fluidounces 50.0 mils
Aromatic Elixir, sufficient to make . . .40 fluidounces 1000 mils
Mix and let stand for four days, then filter, if necessary.
41. ELIXIR SEX lODORUM
Elixir of Six Iodides
Arsenic Iodide 2 grains 0.12 Gm.
Mercuric Iodide 2 grains 0.12 Gm.
Manganese Iodide 32 grains 1.85 Gm.
Sodium Iodide 320 grains 18.50 Gm.
Potassium Iodide 320 grains 18.50 Gm.
Glycerin of Ferrous Iodide 30 minims. 1.50 mils
Sodium Hypophosphtie a sufficient quantity
Aromatic Elixir, sufficient to make . . 40 fluidounces 1000 mils
Add the iodides to the elixir, dissolve by agitation, and add
sufficient sodium hypophosphite to decolorize the liquid. Filter.
42. ELIXIR SODII SALICYLATIS COMPOSITUM
Compound Elixir of Sodium Salicylate
Sodium Sulphate 10 ounces 250.0 Gm.
Sodium Salicylate 800 grains 45.5 Gm.
Magnesium Sulphate . . ; 9 ounces 225.0 Gm.
Lithium Benzoate 400 grains 22.75 Gm.
Tincture of Nux Vomica 2 fluidounces 50.0 mils
Solution of Carmine 6 fluidrachms 18.0 mils
Distilled Water 12 fluidounces 300.0 mils
Simple Elixir, sufficient ot make .... 40 fluidounces 1000 mils
Dissolve the salts in the distilled water and 20 fluidounces
(500 mils) of simple elixir by trituration, add the tincture of nux
vomica and solution of carmine and sufficient simple elixir to
make 40 fluidounces (1000 mils). Filter, if necessary.
43. ELIXIR TERPINI HYDRATIS ET CODEIN/E
Elixir of Terpin Hydrate and Codeine
Terpin Hydrate, in fine powder 320 grains 18.3 Gm.
Codeine Phosphate 40 grains 2.3 Gm.
hillside 10 grains 0.6 Gm.
Tincture of Fresh Sweet-Orange Peel 1% fluidounces 31.5 mils
Alcohol (95%) 13 fluidounces 325.0 mils
Glycerin 20 fluidounces 500.0 mils
Elixir of Orange, sufficient to make . . 40 fluidounces 1000 mils
IS THE CANADIAN' FORMULARY
Dissolve the terpin hydrate, codeine phosphate and gluside
in the alcohol with a gentle heat, add the tincture of orange,
glycerin and enough elixir of orange to make 40 fiuidounces
(1000 mils).
Note. — Each fluidrachm contains terpin hydrate 1 grain (0.065 Gm.)
and codeine phosphate % grain (0.008 Gm.)
44. ELIXIR TERPIN! HYDRATIS ET HEROIN/E
Elixir of Terpin Hydrate and Heroine
Terpin Hydrate 320 grains 18.3 Gm.
Heroine Hydrochloride 13^ grains 18.3 Gm.
Gluside 10 grains 0.6 Gm.
Tincture of \'anilla (1 in 10) V/i fluidrachms 4.0 mils
Alcohol (95°) 15 fiuidounces 375.0 mils
Glycerin 20 fiuidounces 375.0 mils
Elixir of Orange, sufficient to make . 40 fiuidounces 1000 mils
Dissolve the terpin hydrate, heroine hydrochloride and the
gluside in the alcohol with gentle heat : add the tincttire of
vanilla, glycerin and lastly enough elixir of orange to make 40
fiuidounces (1000 mils)..
Note. — Each fluidrachm contains terpin hydrate 1 grain (0.065 Gm.)
and heroine hydrochloride 1/24 grain (0.025 Gm)
45. ELIXIR VIBURNI COMPOSITUM
Compound Elixir of Crampbark
Fluid Extract of Hydrastis I)/ fiuidounces 37.5 mils
Fniid Extract of Viburnum Opulus . 3 fiuidounces 75.0 mils
Fluid Extract of Scutellaria V/z fiuidounces 37.5 mils
Fluid Extract of Mitchella Repens. .V/z fiuidounces 37.5 mils
Aromatic Syrup of Licorice 6 fiuidounces 150.0 mils
Aromatic Elixir, sufficient to make. . 40 fiuidounces 1000.0 mils
Mix the fiuid extracts ; then add the aromatic syrup of lico-
rice and agitate, then add the aromatic elixir. Filter through
paper sprinkled with talc, if necessary.
46. EMULSIO lODOFORMI
Emulsion of Iodoform
Iodoform 10 parts
Glycerin 70 parts
Distilled Water 20 parts
Rub the iodoform to a smooth paste with the glycerin, then
add the water and continue stirring until a uniform product re-
sults.
47. EMULSIO OLEI MORRHU/E
Emulsion of Cod Liver Oil
Col Liver Oil 10 fiuidounces 500.0 mils
Acacia, in fine powder 2>^ ounces 125.0' Gm.
Solution of Gluside 1 fiuidrachm 7.0 mils
or Tolu Syrup 2 fiuidounces 100.0 mils
Flavouring to suit (see No. 108).
Distilled Water sufficient to make . . 20 fiuidounces 1000 mils
THE CANADIAN FORMULARY 19
Prepare a primary emulsion in the following manner;
Place the powdered acacia in a perfectly dry and clean
Wedgwood mortar, then add the oil (pouring it upon the acacia
rather than about it) and triturate until a homogenous mix-
ture results. Then add. all at once, twice as much water
as acacia, (the water having a temperature of not less than 90°F.
32° C.) and stir briskly with the pestle until a thick creamy
emulsion results.
To the primary emulsion thus prepared, add the desired fla-
vouring materials, also the solution of gluside, or tolu syrup,
under constant stirring and likewise enough water to make 20
fluidounces (1000 mils.)
Note. — The hypophosphites of calcium or sodium or other water-
soluble salts can be included in this emulsion, by dissolving them in the
water used in diluting the primary emulsion.
48. EMULSIO OLEI MORRHU/E CUM FERRI PHOSPHATO
Emulsion of Cod Liver Oil with Phosphate of Iron
Cod Liver Oil 20 fluidounces 500 mils
Soluble Ferric Phosphate 240 grains 13.8 Gm.
Powdered Acacia 5 ounces 125.0 Gm.
Syrup of Orange 2y2 fluidounces 62.5 mils
Syrup of Tolu 2^ fluidounces 62.5 mils
Distilled water, sufficient to make ... 40 fluidounces 1000 mils
Prepare a primary emulsion of the cod liver oil, as directed
under emulsio olei morrhuae, then add the syrups, under con-
stant stirring. Dissolve the soluble ferric phosphate in 3^^ fluid-
ounces (87.5 mils) of water, and add this, under'stirring, to the
mixture, and follow with sufficient water to make 40 fluidounces
(1000 mils).
Each fluidounce contains 6 grains (0.4 Gm.) of ferric phos-
phate.
49. EMULSIO OLEI MORRHU/E CUM PEPSINO
Emulsion of Cod Liver Oil witli Pepsin. Phosphatic Emulsion.
Cod Liver Ol 144 fluidounces 4080.0 mils
The Yolks of twenty-four hen's eggs
Glycerin 24 fluidounces 680.0 Gm.
White Sugar 40 ounces 1174.0 Gm.
Compound Powder of .\cacia AVy ounces 128 Gm.
Lime Water 75 fluidounces 2040.0 mils
Diluted Phosphoric Acid 9 fluidounces 255.0 mils
Essence of Pepsin 24 fluidounces 610.0 mils
Flavour, as desired (See No. 108) . . 3 fluidrachms 9.0 mils
Rub the yolks of eggs in a mortar (whites of half this number of
eggs maybe added with advantage) until a smooth paste results;
20 THE CANADIAN" FORMULARY
add the glycerin and stir briskly. Add the compound powder of
acacia, then the cod liver oil in portions of about 8 fluidounces
(230 mils) at a time. When the oil is emulsified add the lime
water containing the sugar in solution and stir vigorously ; then
add the diluted phosphoric acid and finally the essence of pepsin.
and stir vigorously for fifteen minutes. Allow the emulsion to
stand for two hours and strain through dairy cloth.
50. ESSENTIA LIMONIS
Essence of Lemon
Oil of Lemon (fresh) 1 fluidounce 25.0 mils
Lemon Peel (freshlv grated) 1 ounce 25.0 Gm.
Alcohol (95%) . . .' 28 fluidounces 700.0 mils
Distilled Water 12 fluidounces 300.0 mils
Magnesium Carbonate 4 drachms 12.5 Gm.
Mix the oil of lemon and the lemon peel with the magnesium
carbonate. Triturate well, then slowly add the alcohol and dis_
tilled water, previously mixed, meanwhile continuing the tritura-
tion ; macerate for 24 hours, then filter and add sufficient of the
mixed alcohol and water to make 40 fluidounces (1000 mils).
51. ESSENTIA PEPSINI
Essence of Pepsin
Glycerin of Pepsin, B. P 4 fluidounces 100.0 mils
■Sfterry 5 fluidounces 125.0 mils
Glycerin 5 fluidounces 125.0 mils
Alcohol (95%) Zy2 fluidounces 87.5 mils
Tincture of Fresh Sweet-Orange Peel 5 fluidrachms 15.5 mils
Distilled Water, sufficient to make . . 40 fluidounces 1000 mils
Mix and filter through paper sprinkled with talc.
52. ESSENTIA PEPSINI PHENOLATA
Phenolated Essence of Pepsin
Phenol 25 grains 1.5 Gm.
Essence of Pepsin, sufficient to make 40 fluidounces 1000 mils
Dissolve the phenol in the essence of pepsin, and filter, if
necessary.
53. ESSENTIA VANILLINI COMPOSITA
Compound Essence of Vanillin
Compound Tincture of Vanillin
(N.F. 1906)
Vanillin 1 10 grains 6.2 Gm.
Coumarin 8 grains 0.5 Gm.
Alcohol (95%) 7y2 fluidounces 187.0 mils
Glycerin 5 fluidounces 125.0 mils
Syrup 5 fluidounces 125.0 mils
Compound Tincture of Cudbear 5 fluidrachms 18.0 mils
Distilled Water, sufficient to make . . 40 fluidounces 1000 mils
THE CANADIAN FORMULARY 21
Dissolve the vanillin and coumarin in the alcohol, add the
glycerin, syrup and tincture of cudbear and finally sufficient
distilled water to make 40 fluidounces (1000 mils).
54. EXTRACTUM BUCHU FLUIDUM
Fluid Extract of Buchu
(U.S.P. 1905)
Buchu Leaves (60 powder) 40 ounces 1000 Gm.
Alcohol 95%, and Water, of each suffi-
cient to make 40 fluidounces 1000 mils
Mix 30 fluidounces (750 mils) of alcohol with 10 fluidounces
(250 mils) of water^ and having moistened the powder with 16
fluidounces (400 mils) of this menstruum, pack it firmly in a cyl-
indrical percolator, then add enough menstruum to saturate the
powder and leave a stratum above it. Macerate for 48 hours, and
continue the percolation process in the usual manner, reserving
the first 34 fluidounces (850 mils) of the percolate, evaporating
the remainder to a soft extract, and dissolving this in the reserved
percolate, and adding sufficient menstruum to make 40 fluid-
ounces '(1000 mils) of fluid extract.
55. EXTRACTUM CASCAR/E SAGRAD/E
AROMATICUM FLUIDUM
Aromatic Fluid Extract of Cascara
Cascara Bark (in coarse powder) ... 80 ounces 2272.0 Gm.
Licorice Root (in coarse powder) . . 10 ounces 284.0 Gm.
Calcined Magnesia 12 ounces 340.0 Gm.
Gluside 40 grains 2.3 Gm.
Sodium Bicarbonate 10 grains 0.65 Gm.
Oil of Coriander 15 minims. 1.0 mils
Oil of Aniseed 20 minims. 1.25 mils
Alcohol (95%) 1 ounce 28.4 mils
Glycerin 24 ounces 682.0 mils
Distilled Water (boiHng) 100 ounces 2840.0 mils
Mix the cascara, licorice and magnesia, and moisten
thoroughly with the water, stirring well. Place the mix-
ture in a suitable, well-covered container and macerate for 24
hours, then pack moderately tight in a percolator, and percolate
with boiling water until exhausted. Evaporate the percolate
over a water-bath (or steam-bath) until it measures 54 fluidounces
(1535 mils). Dissolve the gluside in 1 flluidcnmce (28.4 mils) of
water with the aid of the sodium bicarbonate. Dissolve the oils
in the alcohol and mix both solutions with the glycerin, then add
the concentrated percolate and shake thoroughly.
22 THE CANADIAN FORMULARY
56. EXTRACTUM SENEG/C FLUIDUM
Fluid Extract of Senega
(U.S. P. 1905)
Senega (No. 40 powder) 40 ounces 1000 Gm.
Solution of Potassium Hydroxide . A% fluidounces 30.0 mils
Alcohol 95%, and Water, of each suffi-
cient to make 40 fluidounces 1000 mils
Mix the solution of potassium hydroxide with 24 fluidounces
(600 mils) of alcohol and 12 fluidounces (300 mils) of water;
continue the percolation process as given under fluid extract
of buchu. using a mixture of alcohol, two parts, with water, one
part, after all of the alkaline menstruum has been used.
57. EXTRACTUM SERPYLLI LIQUIDUM
Liquid Extract of Wild Tliyme
Wild Thyme, in No. 40 powder 20 ounces 1000 Gm.
Glycerin 3 fluidounces 145.0 Gm.
Alcohol, 95%, and A\'ater, of each suffi-
cient to make 20 fluidounces 1000 mils
Follow the instructions given under extractum thymi
liquidum, and continue the percolation process in the usual man-
ner, to make 20 fluidounces (1000 mils) of liquid extract. "
58. EXTRACTUM THYMI LIQUIDUM
Liquid Extract of Garden Thyme
Garden Thyme, in No. 40 powder ... .20 ounces 1000 Gm.
Glycerin 3 fluidounces 145.0 mius
Alcohol 95%, and Water, of each suffi-
cient to make 20 fluidounces 1000 mils
Mix the glycerin with 4 fluidounces (200 mils) of alcohol
and 7 fluidounces (350 mils) of water. Moisten the powder with
9 fluidounces (450 mils) of the mixture, and set aside in a cov-
ered vessel for twelve hours. Then pack the moistened drug
firmly in a cylindrical percolator, and add the remainder of the
mixture, and follow with a menstruum of alcohol, one volume, and
water, two volumes. Continue the percolation process in the
usual manner, to make 20 fluidounces (1000 mils) of liquid ex-
tract.
59. GARGARISMA CHLORI
Chlorine Gargle
Powdered Potassium Chlorate 4 drachms 2.75 Gm.
Hydrochloric Acid 120 minims. 13.0 mils
Distilled Water, sufficient to make . . 20 fluidounces 1000 mils
Add the hydrochloric acid to the potassium chlorate in a
large bottle ; when the gas given ofT has displaced the air, add
the water in portions, corking and shaking the bottle after each
addition.
THE CANADIAX FORMULAKY .23
60. GLYCERINUM BELLADONN>E
Glycerin of Belladonna
Green Extract of Belladonna 1 ounce 25.0 Gm.
Boiling Distilled Water 1 fluidrachm 3.5 mils
Glycerin, sufficient quantity to make . . 2 fluidounces 50.0 mils
Rub together in a warm mortar the extract of belladonna and
the boiling distilled water to produce a smooth paste ; then add
sufficient glycerin to make 2 fluidounces (50.0 mils.)
61. GLYCERINUM BISMUTH!
Glycerin of Bismuth
Bismuth and Ammon. Citrate .11 ounces 308 grains 322.5 Gm.
Glycerin 10 fluidounces 250.0 mils
Strong Solution of Ammonia a sufficient quantity
Distilled Water, sufficient to make . .40 fluidounces 1000 mils
Triturate the bismuth and ammonium citrate with 8 fluid-
ounces (200 mils) of distilled water, and 3 fluidounces (150 mils)
glycerin, and gradually add to it just enough strong solution of
ammonia to dissolve the salt and produce a neutral solution.
Then add the remainder of the glycerin and sufficient distilled
water to make 40 fluidounces (1000 mils).
Note. — Each fluidrachm contains 16 grains (1 Gm.) of bismuth and
ammonium citrate.
62. GLYCERINUM FERRI lODIDI
Glycerin of Ferrous Iodide
Iron (in wire) 2^^ ounces 125.0 Gm.
Iodine 6 ounces 405 grains 414.0 Gm.
Glycerin 10 fluidounces 500.0 mils
Sulphurous Acid, B. P 125 minims. 13.0 mils
Distilled Water, sufficient to make . . 20 fluidounces 1000 mils
Mix the iron and iodine in a flask with 8 fluidounces (200
mils) of distilled water. Shake the mixture occasionally, check-
ing the reaction, if necessary, by the affusion of cold water, and
when the solution has acquired a greenish color and has lost the
odor of iodine, heat it gently to the boiling point; add at once
2 fluidounces (50 mils) of glycerin and filter the solution into
the remainder of the glycerin. Then add the sulphurous acid and
sufficient glycerin to make 20 fluidounces (1000 mils) ; mix
thoroughly.
Note. — This preparation should be kept in small, well-filled, well-
corked, colorless glass bottles, in a place accessible to light. Each fluid-
ounce contains 220 grains ferrous iodide. 1 volume mixed with 4 vol-
umes of simple syrup will furnish a preparation similar to syrup of fer-
rous iodide, B. P.
24 THE CANADIAN FORMULARY
63. GLYCERINUM FERRI PHOSPHATIS CUM QUININA
ET STRYCHNINA
Glycerin of Phosphate of Iron with Quinine and Strychnine.
Iron Wire 750 grains 45.0 Gm.
Concentrated Phosphoric Acid, B. P. 15 fluidounces 375.0 mils
Strychnine 50 grains 2.8 Gm.
Quinine Sulphate 1300 grains 73.0 Gm.
Glycerin 24 fluidounces 600.0 mils
Distilled Water, sufficient to make.. 40 fluidounces 1000 mils
Place the iron wire and the phosphoric acid (previously dilut-
ed with 4 fluidounces (100 mils) of distilled water) in a flask, plug
the neck with cotton wool and heat gently till the iron is dissolved
Dissolve the quinine and strychnine in the glycerin with the aid
of heat, and while hot, filter the solution of ferrous phosphate
into it and pass sufficient distilled water through the filter to
make 40 fluidounces (1000 mils).
Note. — One volume of this glycerin mixed with 4 volumes of simple
syrup will furnish a preparation similar to syrup triple phosphates, B.P.
64. GLYCERINUM HEROINI COMPOSITUM
Compound Glycerin of Heroin
Heroin Hydrochloride 20 grains 1.15 Gm.
Ammonium Hypophosphite 640 grains 36.6 Gm.
Fluid Extract of Hyoscyamus 320 minims. 18.3 mils
Fluid Extract of \\hite Pine 2| fluidounces 66.5 mils
Soluble Tincture of Tolu 2 fluidounces 50.0 mils
Syrup of Wild Cherry Bark 12 fluidounces 300.0 mils
Glycerin, sufficient to make 40 fluidounces 1000 mils
Dissolve the heroin hydrochloride and the ammonium hypo-
phosphite in the ^Oiub"- . ^. > i -■ -
bark and 10 fluidounces (250 mils) of glycerin. Add the fluid
extracts and then sufficient glycerin to make 40 fluidounces (1000
mils).
65. GLYCERINUM lODI
Glycerin of Iodine
Iodine, resublimed 1 part ^
Glycerin 50 parts
Dissolve the iodine in the glycerin with the aid of a gentle
heat.
Note. — This forms a useful pigment; the skin does not harden or
peel by repeated applications.
THE CANADIAN FORMULARY 25
66. INFUSUM BUCHU CONCENTRATUM
Concentrated Infusion of Buchu
(B.P.C. 1907)
Buchu Leaves 40.0 parts
Tincture of Buchu 22.5 parts
Alcohol, 95% 10.0 parts
Chloroform Water ( 1 in 1000) sufficient to make . . . 100.0 parts
Prepare by the macero-expression process of the British
Pharmaceutical Codex for concentrated infusions.
Dose, 1 to 2 fluidrachms (4 to 8 mils).
67. LAC FERMENTATUM
Fermented Milk
"Kumyss."
(N.F. 1906)
Cows' Milk (fresh) 20 fluidounces 1000 mils
Yeast (semi-liquid) 45 minims 5.0 mils
Sugar 5 drachms 35.0 Gm.
Dissolve the sugar in the milk contained in a strong bottle,
add the yeast, cork the bottle securely, and keep it at a tempera-
ture between 74° and 90° F. for six hours, then transfer it to a
cold place, preferably a refrigerator.
Note. — 24 grains of compressed yeast, triturated vvitii a little milk,
may be used in place of the semi-liquid yeast.
68. LAC HUMANISATUIVI
Humanized Milk
(N.P. 1906)
Milk Powder 100 grains 6.5 Gm.
Cows' Milk (fresh) 2 fluidounces 56.8 mils
Sweet Cream (fresh) 4 fluidrachms 14.0 mils
Distilled Water 2 fluidounces 56.8 mils
Triturate the milk powder with the water, transfer the mix-
ture into a bottle containing the milk and cream, and immerse the
bottle in water heated to 100° F. (38°C.) for fifteen minutes; then
pour the mixture into a suitable vessel, in which heat it quickly
to boiling and then immediately allow it to cool to the body tem-
perature.
Note. — Should be freshly prepared. If the directions are carefully
followed the milk will be well peptonized and the pancrcatin of the milk
powder rendered sterile.
69. LINIMENTUM ALBUM
White Liniment. Stokes' Liniment
Acetic Turpentine Liniment
(N.F. 1906)
Oil of Turpentine 3 fluidounces 85.2 mils
Fresh Hen's Egg 1 (one) 1 (one)
Oil of Lemon 60 minims. 3.5 mils
Acetic Acid 300 minims. 17.5 mils
Rose Water 2l^ fluidounces 71.0 mils
26 THE CANADIAN FORMULARY
Triturate or beat the contents of the fresh hen's egg with the
oils in a mortar until they are thoroughly mixed. Then incor-
porate the acetic acid and rose water. Shake the mixture, when
it is to be dispensed.
70. LINIMENTUM AMMONII lODIDI
Liniment of Ammonium Iodide
Strong Solution of Ammonia 5 fluidounces 50.0 mils
Tincture of Iodine 5 fluidounces 50.0 mils
Glycerin 5 fluidounces 50.0 mils
Tincture of Camphor 5 fluidounces 50.0 mils
Mix by agitation.
Note. — On standing, the liquid will become colorless, usually with
a slight deposit, which may be separated by filtration.
71. LINIIVIENTUM IVIENTHOLIS
Menthol Liniment
Menthol 2 ounces 50.0 Gm.
Chloroform 8 fluidounces 200.0 mils
Olive Oil, sufficient to make 40 fluidounces 1000 mils
Mix and agitate until the menthol is dissolved.
Note. — The Colonial Addendum of the British Pharmacopoeia per-
mits the use of oleum sesami (oil of benne) in North American Colonies,
in HKiking the official liniments, ointments and plasters, for which the
B.P. orders that olive oil shall be used.
72. LINIMENTUM MENTHOLIS COMPOSITUM
Compound Menthol Liniment.
Menthol 1 ounce 10.0 Gm.
Liniment of Ammonium Iodide 49 fluidounces 490.0 mils
Mix and agitate until the menthol is dissolved.
73. LINIMENTUM METHYLIS SALICYLATIS COMPOSITUM
Compound Liniment of Methyl Salicylate
Linimentum Betulae Compositum
Compound Liniment of BetuI
Menthol 1 ounce 50.0 Gm.
Hydrated Chloral 1 ounce 50.0 Gm.
Alcohol (95%) 2 fluidounces 100.0 mils
Tincture of Cannabis Indica 2 fluidounces 100.0 mils
Essential Oil of Camphor 4 fluidounces 200.0 mils
Methyl Salicylate, sufficient to make . .20 fluidounces 1000 mils
Mix intimately to make a homogeneous liquid.
74. LIQUOR AMMONII VALERIANATIS
Solution of Valerianate of Ammonium
Valerianic Acid 3 parts
Ammonium Carbonate, a sufficient quantity.
Alcoholic Extract of Valerian 2 parts
Distilled Water, sufficient to make 100 parts
THE CANADIAN FORMULARY 27
Add the acid to the waier and neutralize carefully with am-
monium carbonate, add the extract of valerian, and let it stand
for 24 hours, then filter.
Dose, 10 to 30 drops in sweetened water.
75. LIQUOR ANTISEPTICUS
Antiseptic Solution
(U. S. P. 1905)
Boric Acid 352 grains 20.0 Gm.
Benzoic Acid 18 grains 1.0 Gm.
Thymol 18 grains 1.0 Gm.
Eucalyptol 4 minims. 0.25 mils
Oil of Peppermint 8 minims. 0.5 mils
Oil of Gaultheria 4 minims. 0.25 mils
Oil of Thyme 1^ minims. 0.1 mils
Alcohol (95%) 10 fluidounces 250.0 mils
Purified Talc 352 grains 20.0 Gm.
Water, sufficient to make 40 fluidounces 1000 mils
Dissolve the boric acid in 24 fluidounces (600 mils) of water
and the benzoic acid in 6 fluidounces (150 mils) of alcohol, and
pour the aqueous solution into the alcoholic solution, then dis-
solve (in a mortar) the thymol in the eucalyptol and oils of pep-
permint, gaultheria and thyme ; thoroughly incorporate the puri-
fied talc, and add with constant trituration to the solution first
prepared. Allow the mixture to stand with occasional agitation,
during forty-eight hours, filter, add 4 fluidounces (100 mils) of
alcohol to the clear filtrate, and a sufficient quantity of water to
make the finished product measure 40 fluidounces (1000 mils).
76. LIQUOR ANTISEPTICUS ALKALINUS
Alkaline Antiseptic Solution
(N.F. 1906)
Potassium Bicarbonate 600 grains 32.0 Gm.
Sodium Benzoate 600 grains 32.0 Gm.
Sodium Biborate 310 grains . 8.0 Gm.
Thymol 4 grains 0.2 Gm.
Eucalyptol 4 minims. 0.2 mils
Oil of Peppermint 4 minims. 0.2 mils
Oil of Wintergreen 7 minims. 0.4 mils
Tincture of Cudbear 300 minims. 16.0 mils
Alcohol (95%) 2^ fluidounces 62.5 mils
Glycerin 10 fluidounces 250.0 mils
Purified Talc 185 grains 10.0 Gm.
Water, sufficient quantity to make . . 40 fluidounces 1000 mils
Dissolve the salts in 23 fluidounces (575 mils) of water, and
the thymol, eucalyptol and oils in the alcohol. Mix the alcoholic
solution with the glycerin and tincture of cudbear, add the solu-
tion of the salts and enough water to make 40 fluidounces (1000
28 THE CANADIAN FORMULARY
mils). Add the talc, shake occasionally during a few days,
then filter.
77. LIQUOR AURl ET ARSENII BROMIDI
Solution of Bromide of Gold and Arsenic
(N.F. 1906.)
Arsenious Acid 10 Grains 2.50 Gm.
Gold Tribromide 13 grains 3.25 Gm.
Bromine Water, Distilled Water, of each
a sufficient quantity to make 10 fluidounces 1000 mils
Introduce the arsenious acid and abo'it Ig fluidounces
(135 mils) of bromine water in a flask and heat gently until all
free bromine has disappeared. Then add bromine water, 20 to
30 drops at a time, until it will be present in slight excess, or un-
til the solution does not become colorless after some time. Trans-
fer the solution to a porcelain capsule, expel the excess of bro-
mine with the aid of gentle heat, dilute it with water to about 9
fluidounces (900 mils) and dissolve in this the tribromide of gold,
adding enough water to make 10 fluidounces (1000 mils).
Ten (10) minims, of this solution contain 3V grain (.002
Gm.) of tribromide of gold and the equivalent of -jV grain
(0.004 Gm.) of tribromide of arsenic.
• Note. — Bromine Water is made by shaking bromine with about
thirty times its weight of water, occasionally during several hours, and
decanting the water from the undissolved bromine.
Average dose, 3 minims. (2 decimils).
78. LIQUOR BORACIS COMPOSITUS
Compound Solution of Borax
Dobell's Solution
(N.F. 1906)
Borax 130 grains 15.0 Gm.
Sodium Bicarbonate 130 grains 15.0 Gm.
Carbolic Acid 25 grains 3.0 Gm.
Glycerin 5^ fluidrachms 35.0 mils
Water, sufficient to make 20 fluidounces 1000 mils
Dissolve the salts in about 10 fluidounces (500 mils) of
water ; then add the glycerin and the carbolic acid, previously
liquefied by warming, and lastly enough water to make 20 fluid-
ounces (1000 mils).
79. LIQUOR BROMO-CHLORAL COMPOSITUS
Compound Solution of Bromo-Chloral
Chloral Hydrate 3>4 ounces 182.75 Gm.
Potassium Bromide 3^ ounces 182.75 Gm.
Tincture of Cannabis Indica 6 fluidrachms 41.65 mils
Tincture of Orange Peel 6 fluidrachms 41.65 mils
THE CANADIAN FORMULARY 29
Henbane Juice 3 fluidounces 165.55 mils
Syrup 334 fluidounces 187.5 mils
Fluid Extract of Licorice 5/2 fluidounce 25.0 mils
Water, sufficient to make 20 fluidounces 1000 mils
Dissolve the potassium bromide and chloral hydrate in 8
fluidounces (400 mils) of water. Mix all the other ingredients,
and add the foregoing solution ; then filter and wash the filtrate
with sufficient water to make 20 fluidounces (1000 mils).
Dose, 3^ to 2 fluidrachms (2 to 8 mils).
80. LIQUOR CARMINI
Solution of Carmine
Carmine, Nr. 40 1 ounce 87 grains 60 Gm.
Solution of Ammonia 7 fluidounces 350 mils
Glycerin 7 fluidounces 350 mils
Water, sufficient to make 20 fluidounces 1000 mils
Triturate the carmine to a fine powder in a wedgwood mor-
tar, gradually add the solution of ammonia, and afterwards the
glycerin under constant trituration. Transfer the mixture to a
porcelain capsule and heat it upon a water-bath, constantly stir-
ing, until the liquid is free from ammoniacal odor. Then cool
and add enough water to make 20 fluidounces (1000 mils).
81. LIQUOR CREOSOTI ET lODI
Solution of Creosote and Iodine
Iodine, resublimed 2 ounces 56.8 Gm.
Creosote 3 fluidounces 85.2 mils
Triturate the iodine in a glass mortar to a fine powder, add
the creosote slowly and continue trituration until solution is
effected.
Note. — This preparation is intended for dental use
82. LIQUOR CRESOLIS
Solution of Cresol
Cresylic Acid (Cresol) 25 fluidounces 625.0 mils
Resin 5 ounces 125.0 Gm.
Potassium Hydroxide 350 grains 25.0 Gm.
Distilled Water, sufficient to make . . 40 fluidounces 1000 mils
Dissolve the resin in the cresylic acid with the aid of heat.
Make a solution of the potassium hydrate by dissolving in two
fluidounces (50 mils) of distilled water. Mix the two solutions,
and heat until saponification takes place. Set aside to cool, and
make up to 40 fluidounces (1000 mils) with water.
30 THE CANADIAN" FORMULARY
83. LIOUOR GLUSIDI
Solution cf Gluside
Solution of Saccharin
(N.F. 1906)
Gluside 640 grains 73.0 Gm.
Sodium Bicarbonate 300 grains 33.0 Gm.
Aclohol (95%) 5 fluidounces 250.0 mils
Water, sufficient to make 20 fluidounces 1000 mils
Dissolve the gluside and the sodium bicarbonate in -13 fluid-
ounces (650 mils) of water, filter the solution, add the alcohol to
the filtrate and pass enough water through the filter to make 20
fluidounces (1000 mils).
Each fluidrachm represents 4 grains (0.26 Gm.) of gluside.
84. LIQUOR HYPOPHOSPHITUM COMPOSITUM
SINE SACCHARO
Compound Solution of Hypophosphltes, without Sugar
Potassium Hypophosphite 320 grains 9.2 Gm.
C^cium Hypophosphite 320 grains 9.2 Gm.
Sodium Hypophosphite 80 grains 2.5 Gm.
Iron Hypophosphite 160 grains 4.5 Gm.
Manganese Hypophosphite 80 grains 2.5 Gm,
Potassium Citrate 300 grains 8.5 Gm.
Citric Acid 100 grains 3.0 Gm.
Quinine (alkaloid) 80 grains 2.5 Gm.
Strychnine (alkaloid) 2^4 grains .064 Gm.
Hypophosphorus Acid (10%) a sufficient quantity
Oil of Sweet Orange 12 minims. 0.4 mils
Alcohol (95%) 10 fluidrachms 15.0 mils
Gluside 25 grains 0.7 Gm.
Glycerin 20 fluidounces 250.0 mils
Distilled Water, sufficient to make . . 80 fluidounces 1000 mils
Dissolve the hypophosphltes of potassium, calcium and so-
dium in 28 fluidounces (350 mils) of boiling distilled water. Dis-
solve the hypophosphltes of iron and manganese, the citrate of
potassium and citric acid, in 8 fluidounces (100 mils) of water
with a gentle heat. Dissolve the alkaloids in a little water with
a sufficient quantity of hypophosphorus acid. Mix these solu-
tions and add the glycerin. Dissolve the gluside and the oil of
orange in the alcohol with gentle heat, and mix with the fore-
going solution, then add sufficient distilled water to make 80
fluidounces (1000 mils).
THE CANADIAN FORMULARY 31
85. LIQUOR lODl DILUTUS
Dilute Solution of Iodine
Iodine 440 grains 50.0 Gm.
Potassium Iodide 600 grains 67.5 Gm.
Distilled Water, sufficient to make . . 20 fluidounces 1000 mils
Dissolve.
86. LIQUOR OPIl SEDATIVUS
Sedative Solution of Opium
Sedative Liquid
Extract of 0]:)ium 1280 grains 72.8 Gm.
Alcohol (95%) 6}i fluidounces 156.0 mils
Water, sufficient to make 40 fluidounces 1000 mils
Dissolve the extract of opium in 16 fluidounces (400 mils) of
boiling water. Cool the solution, add the alcohol and cold water,
filter and add sufficient water to make 40 fluidounces (1000 mils).
Note. — Each fluidrachm represents 4 grains of extract of opium.
86a. LIQUOR PECTORALIS
Pectoral Solution
Anisated Spirit of Ammonia 1 fluidounce 2.5 mils
Syrup of Althea 6 fluidounces 15.0 mils
Distilled Water, sufficient to make . . .40 fluidounces 1000 mils
Mix.
87. LIQUOR POTASSII CITRATIS
Solution of Potassium Citrate
(U. S. P. 1905)
Potassium Bicarbonate 124 grains 40.0 Gm.
Citric Acid 93 grains 30.0 Gm.
Distilled Water, sufficient to make . .3)^ fluidounces 500.0 mils
Dissolve the potassium bicarbonate and the citric acid each
in 10 fluidrachms (150 mils) of distilled water. Filter the solu-
tions separately and wash the filters with enough distilled water
to obtain, in each case, 15 fluidrachms (225 mils). Finally mix
the two solutions, and when effervescence has nearly ceased,
tarnsfer the liquid to a bottle.
Dose, 4 fluidrachms.
Note. — This preparation should be freshly made when wanted.
88. LIQUOR SAPONIS ANTiSEPTICUS
Antiseptic Soap Solution
Oleic Acid 14 fluidounces 350 mils
Potassium Hvdroxide in solution (1 in 1), a sufficient quantity.
Alcohol (95%) 6 fluidounces 150 mils
Oil of Lavender 40 minims. 2.5 mils
Ether, sufficient to make 40 fluidounces 1000 mils
32 THE CANADIAN FORMULARY
Mix the oleic acid and alcohol and neutralize with the solu-
tion of potassium hydroxide, using phenolphthalein solution as
an indicator. Cool and add the oil of lavender, then add suffi-
cient ether to make 40 fluidounces (1000 mils).
89. LIQUOR OLEl SANTALI FLAVI COMPOSITUS
Compound Solution of Sandal Oil
Oil of Sandal 2 fluidounces 50.0 mils
Oil of Cubebs 1 fluidounce 25.0 mils
Oil of Copaiba 6 fluidrachms 18.75
Oil of Pimenta 30 minims. 1.5 mils
Is
Is
Oil of Cassia 30 minims. 1.5 m
Tincture of Buchu 6 fluidounces 150.0 m
Concentrated Infusion of Buchu 6 fluidounces 150.0 mils
Alcohol (95%) 8 fluidounces 200.0 mils
Solution of Potassium Hydroxide .... 6 fluidounces 150.0 mils
Magnesium Carbonate 1 Av. ounce 25.0 mils
Distilled Water 3 fluidounces 75.0 mi
Is
Boil the solution of potash and mix with the oils ; let stand
for two days, add the distilled water, and shake well (if not
saponified, boil with the addition of a little more solution of pot-
ash). Cool and add the tincture and infusion of buchu, the alco-
hol and lastly the magnesium carbonate. IMix well, let stand for
3t hours and filter.
GO. LIQUOR SODII HYDROXIDI
Solution of Sodium Hydroxide
Solution of Soda
Sodium Hydroxide 5 parts
Distilled Water, sufficient to make 100 parts
Dissolve the sodium hydroxide in the distilled water and pre-
serve in a well-stoppered, green glass bottle.
91. LIQUOR ZINGIBERJS
Solution of Ginger
Soluble Essence of Ginger
Strong Tincture of Ginger (1 in 2) . . . 10 fluidounces 500.0 mils ,
Purified Talc 634 ounces 335.0 mils
A\'hite Sugar 6^ ounces 335.0 mils
Distilled Water, sufficient to make . . 20 fluidounces 1000 mils
Triturate the tincture of ginger with the sugar and purified
talc, add the distilled water, shake and filter, returning the
first portions of filtrate to the filter, until a clear liquid is ob-
tained.
THE CANADIAN FORMULARY 33
92. LOTIO CALAMIN>E
Calamine Lotion
Levigated Calamine 40 grains 2.6 Gm.
Zinc Oxide 20 grains 1.3 Gm.
Glycerin 20 minims. 1.5 mils
Lime Water, sufficient to make 1 fluidounce 28.4 mils
Elutriate the calamine and zinc oxide by triturating them in
a mortar with successive portions of the lime water and decant-
ing from the silicious matter, then add the glycerin.
93. LOTIO CALCIS SULPHURAT/E
Sulphurated Lime Lotion
Vleminck's Solution for Lotion)
(N. F. 1906)
Slaked Lime 3 ounces 132 grains 165.0 Gm.
Sublimed Sulphur 5 Av. ounces 250.0 Gm.
Distilled Water, sufficient to make . . 20 fluidounces 1000 mils
Mix the slaked lime with the sulphur and add the mixture
gradually to 33 fluidounces (1650 mils) of boiling water. Then
boil the whole under constant stirring until it measures 20 fluid-
ounces (1000 mils) ; strain, and having allowed the solution to
become clear by standing in a well-stoppered bottle, decant the
clear brown liquid and keep it in completely filled and well-
stoppered bottles.
93a. LOTIO OPIl COIV1POSITA
Fuller's Lotion
Sodium Bicarbonate 2^/2 ounces 62.5 Gm.
Tincture of Opium 3^ fluidounces 83.3 mils
Glycerin 6| fluidounces 166.0 mils
Distilled Water, sufficient to make . . .40 fluidounces 1000 mils
Mix.
94. LOTIO SULPHURIS COMPOSITA
Compound Sulphur Lotion
Zinc Sulphate 600 grains 34.0 Gm.
Sulphurated Potash 600 grains 34.0 Gm.
Precipitated Sulphur 600 grains 34.0 Gm.
Glycerin 10 fluidrachms 32.0 mils
Distilled Water 20 fluidounces 500.0 mils
Rose W^ater, suffiicient to make .... 40 fluidounces 1000 mils
Dissolve the zinc sulphate in 10 fluidounces (250 mils) of
distilled water and filter. Dissolve the sulphurated potash in 10
fluidounces (250 mils) of distilled water, and filter. Mix the two
solutions, by slowly pouring the solution of zinc sulphate into
the solution of sulphurated potash. Triturate the sulphur with
the glycerin, then gradually add, under constant trituration, the
foregoing solution, and sufficient rose water to make 40 fluid-
ounces (1(XX) mils). .
34 THE CANADIAX FORMULARY
95. MAGMA MAGNESIA
Magnesia Magma
(Milk of Magnesia)
(N. F. 1906)
Magnesium Sulphate 10 ounces 250.0 Gm.
Sodium Hydroxide 3 ounces 81.0 Gm.
Distilled Water, sufficient to make . . .40 fluidounces 1000 mils
Dissolve the magnesium sulphate in 160 fluidounces (4000
mils) of water, and the sodium hydroxide in another portion of
160 fluidounces (4000 mils) of water; filter the solutions.
Pour the sodium hydroxide slowly in a thin stream into the mag-
nesium sulphate solution with constant stirring. Allow the pre-
cipitate to subside and decant the clear liquid. Wash the mag-
ma several times with water by decantation until the washings
are free from saline taste. Transfer the magma to a muslin
strainer and allow to drain without pressing. Then re-transfer
it to suitable vessels and add sufficient water to make 40 fluid-
ounces (1000 mils) and mix thoroughly by stirring.
Eaich fluidrachm contains about three grains (0.195 Gm.) of
magnesium hydroxide.
Note. — Tlie water used in this preparation must be free from or-
ganic matter or the magma will become discolored.
96. MISTURA BUTYL-CHLORAL
• Mixture of Butyl-Chloral
Butyl-Chloral Hydrate 80 grains 9.0 Gm.
Glycerin 5 fluidrachms 35.0 mils
Distilled Water, sufficient to make . . .20 fluidounces 1000 mils
Mix and dissolve. Dose, one fluidounce (30 mils).
97. NEBULA MENTHOLIS COMPOSITA
Compound Menthol Spray
Camphor 30 grains 3.4 Gm.
Menthol 8 grains 1.0 Gm.
Thymol 4 grains 0.5 mils
Eucalyptol 8 grains 1.0 Gm.
Oil of Wintergreen 30 grains 3.4 mils
Hydrastine Ys grain .015 Gm.
Liquid Parafifin (colorless) sufficient
to make 20 fluidounces 1000 mils
Mix intimately, to make a homogeneous liquid.
98. OLEUM RICINI AROMATICUM
Aromatic Castor Oil
"Sweet Castor Oil"
Gluside 7>4 grains 0.4 Gm.
Chloroform 150 minims. 8.0 mils
Oil of Pimenta 75 minims. 4.0 mils
Gil of Cassia 75 minims. 4.0 mils
THE CANADIAN FORMULARY 35
Oil of Cloves 75 minims. 4.0 mils
Castor Oil, sufficient to make 40 fluidounces 1000 mils
Dissolve the gluside in the chloroform : then add the oils
(which have been previously mixed) and shake vigorously.
99. PASTA lODI ET AMYLI
Iodine and Starch Paste
Starch, in powder 1 ounce 10 Gm.
Glycerin 2 ounces 20 Gm.
Water 2 fluidounces 60 mils
Dilute Solution of Iodine 1 ounce 10 mils
Boil the starch in the glycerin and water, and when nearly
cold, add the solution of iodine and mix thoroughly.
100. PEPSINUM SACCHARATUM
Saccharated Pepsin
(U. S. P. 1905)
Pepsin 10 parts
Sugar of Milk, recently dried 90 parts
Triturate the pepsin with the sugar of milk to a fine, uniform
powder and keep the product in well-stoppered bottles.
101. PIGIVIENTUIVI lODI COMPOSITUIVl
Compound Iodine Paint
Mandl's Solution
Iodine 5 grains 0.3 Gm.
Menthol 5 grains 0.3 Gm.
Potassium Iodide 15 grains 1.0 Gm.
Glycerin 1 fluidounce 28.4 mils
Triturate until a perfect solution is obtained.
102. PULVrS ACACi>e COIVIPOSITUS
Compound Acacia Powder
Powdered Acacia 5 parts
Powdered Tragacanth 5 parts
Powdered Starch 5 parts
Powdered Sugar 5 parts
Pow^dered Boric Acid 1 part
Triturate the powders together until thoroughly mixed.
Note. — Recommended as an emulsifying agent.
103. PULVIS ACETANILDI COIVIPOSITUS
Compound Powder of Acetanilide
(N. F. 1896)
Acetanilide 7 ounces 70 Gm.
Cafifeine 1 ounce 10 Gm.
Sodium Bicarbonate .-.•... 2 ounces 20 Gm.
Reduce the ingredients separately to fine powders and mix
them thoroughly,
'i-- Dose, 3 to 5 grains (0.2 to 0.33 Gm.)
36 THE CANADIAN FORMULARY
104. PULVIS ALOES ET CANELL>E
Powder of Aloes and Canella
Hiera Picra
Socotrine Aloes, in fine powder 4 parts
Canella, in fine powder 1 part
Mix them intimately.
105. PULVIS ANTISEPTICUS SOLUBILIS
Soluble Antiseptic Powder
(N. F. 1906)
Salicylic Acid 75 grains 5.0 Gm.
Carbolic Acid 15 grains 1.0 Gm.
Eucalyptol 15 grains 1.0 Gm.
Menthol 15 grains 1.0 Gm.
Thymol 15 grains 1.0 Gm.
Zinc Sulphate 4 ounces 125.0 Gm.
Boric Acid 30 ounces 866.0 Gm.
Triturate the salicylic acid and zinc sulphate to a very fine
powder, add the carbolic acid, eucalyptol, menthol and thymol,
and continue the trituration, adding the boric acid, in small por-
tions at a time, until a uniform impalpable powder is obtained.
106. PULVIS BENZOATIS COMPOSITUS
Compound Benzoate Powder
Skeenes' Mixture
Benzoic Acid 1 part
Potassium Bicarbonate 3 parts
Powdered Sugar 12 parts
Triturate the benzoic acid and potassium bicarbonate separ-
ately in a hot mortar for ten minutes, then add the powdered
sugar, previously warmed, and triturate all together, keeping
the mortar continuously hot.
Dose, ^ to 1 drachm (2 to 4 mils).
107. PULVIS LACTIS COMPOSITUS
Compound Milk Powder
Humanizing Milk Powder
(N. F. 1906)
Compound Pancreatic Powder 35 parts
Sugar of Milk, in fine powder 965 parts
Mix intimately.
Note. — This preparation is intended for convenient use in preparing
humanized milk. A teaspoonful approximates about 100 grains (8.5 Gms.)
THE CANADIAN FORML'LARY 37
108. PULVIS PANCREATICUS COMPOSITUS
Peptonizing Powder
(N. F. 1906)
Pancreatin 20 parts
Sodium Bicarbonate 80 parts
Mix them by trituration'.
Note. — To peptonize 16 fluidounces of fresh cows' milk, add 25
grains of compound pancreatic powder to four fluidounces of tepid water
contained in a suitable flask, and afterwards add 16 fluidounces of fresh
cows' milk, previously heated to 100° F. Maintain the mixture at this
temperature for thirty minutes, then transfer the flask to a cold place.
Milk thus peptonized should not be used when it has been kept over 24
hours, or when it has developed a bitter taste.
109. PULVIS PEPSINI COMPOSITUS
Compound Powder of Pepsin
Pulvis Digestivus
(N. F. 1906)
Saccharated Pepsin 225 grains 15.0 Gm.
Pancreatin 225 grains 15.0 Gm.
Diastase 15 grains 1.0 Gm.
Lactic Acid 15 minims. 1.0 mils
Hydrochloric Acid 30 minims. 2.0 mils
Sugar of Milk, in powder 960 grains 66.0 Gm.
Add the acids gradually to the sugar of milk, and triturate
until thoroughly mixed. Mix the pepsin, pancreatin and dias-
tase and then incorporate this mixture by trituration with the
sugar of milk. Finally rub the mixture through a hair-sieve, and
preserve the powder in bottles.
110. PULVIS PRO MISTURA CRETA
Powder for Chalk Mixture
Prepared Chalk 50 grains 5.0 Gm.
Powdered Tragacanth 7 grains 0.7 Gm.
Powdered Sugar 100 grains 10.0 Gm.
Mix the powders and keep in a well-stoppered bottle.
When required for making chalk mixture use 40 grains (2.6
Gm.) of the powder to each fluidounce (28.4 mils) of cinnamon
water.
111. PULVIS SANTONIN! COMPOSITUS
Compound Powder of Santonin.
Santonin 125 grains 1.25 Gm.
Sub-Chloride of Mercury 125 grains 1.25 Gm.
Rhubarb, in fine powder 200 grains 2.00 Gm.
Sugar, in fine powder •. 50 grains 0.50 Gm.
Oil of Peppermint 15 minims. 0.20 mils
Mix intimately.
Note. — 4 grains (0.26 Gm.) contain 1 grain (0.065 Gm.) each of
Santonin and Calomel, and 1 3/5 grains (0.1 Gm.) of Rhubarb.
38 THE CANADIAN" FORMULARY
112. SAL CAROLINUM FACTITIUM
Artificial Carlsbad Salt
(N. F. 1906)
Dried Sodium Sulphate 44 parts
Potassium Sulphate * 2 parts -
Sodium Chloride, purified 18 parts
Sodium Bicarbonate 36 parts
Triturate the ingredients, previously well dried, to a fine, uni-
form powder. The dried sodium sulphate is prepared by slowly
drying the crystalline salt until it has lost one-half of its weight.
Note. — Fifty-three grains dissolved in one pint of water gives a so-
lution, that is similar to Carlsbad (Sprudel) Water, in its essential con-
stituents.
113. SAL LITHIA ALKALINUS
Alkaline Lithia Salt
Caffeine , , , . 20 parts
Lithium Carbonate .- 100 parts
Sodium Bicarbonate 200 parts
Potassium Bicarbonate 200 parts
Tartaric Acid 400 parts
Powdered Sugar 700 parts
Reduce each to a fine powder separately, then mix them
intimately with light trituration.
114. SAPORES PRO EMULSIONIBUS
Flavours for Emulsions
(N. F. 1906)
The quantities given below are intended for 40 fiuidounces
(1000 mils) of finished Emulsion of Cod Liver Oil.
1. Oil of Gaultheria 78 minims. 4.0 mils
2. Oil of Gaultheria 40 minims. 2.0 mils
Oil of Sassafras 40 minims. 2.0 mils
3. Compound Spirit of Orange 30 minims. 1.5 mils
4. Oil of Gaultheria 40 minims. 2.0 mils
Oil of Bitter Almond 4 minims. 0.25 mils
Oil of Coriander 4 minims. 0.25 mils
5. Oil of Gaultheria .30 minims. 1.5 mils
Oil of Sassafras 30 minims. 1.5 mils
Oil of Bitter Almond 4 minims. 0.25 mils
.6. Oil of Gaultheria 48 minims. 2.5 mils
Oil of Bitter Almond 48 minims. "2.5 mils
THE CANADIAN FORMULARY 39
115. SPIRITUS ASPARAGI COMPOSITUS
Compound Spirit of Asparagus
Asparagus Seed *. 1 ounce 28.4 Gm.
Parsley Seed 1 ounce 28.4 Gm.
Black Haw 2^ ounces 64.0 Gm.
Henbane Leaves 100 grains 6.5 Gm.
Compound Spirit of Orange 4 fluidrachms 15.0 mils
Diluted Alcohol, a sufficient quantity.
Reduce the drugs to a powder and percolate with diluted
alcohol to make 15^ fluidounces (425 mils) to which add the
compound spirit of orange.
115a. SPIRITUS AMMONI/E ANISATUS
Anisated Spirit of Ammonia
Anethol 3 parts
Alcohol (90%) 72 parts
Solution of Ammonia, B. P 15 parts
Mix in order named.
116. SPIRITUS AMYGDAL/E AMAR/E
Spirit of Bitter Almond
Essence of Ratafia
(U. S. P. 1905)
Oil of Bitter Almond 70 minims. 10 mils
Alcohol (95%) 16 fluidounces 800 mils
Distilled Water, sufficient to make ...20 fluidounces 1000 mils
Dissolve the oil in the alcohol and add enough water to
make 20 fluidounces (1000 mils).
117. SPIRITUS AURANTII
Spirit of Orange
Fresh Oil of Sweet-Orange Peel 1 fluidounce 10 mils
Deodorized Alcohol 9 fluidounces 90 mils
Mix.
118. SPIRITUS AURANTII COIVIPOSITUS
Compound Spirit of Orange
(U. S. P. 1905)
Oil of Orange Peel 4 fluidounces 200 mils
Oil of Lemon 1 fluidounce 50 mils
Oil of Coriander 3^ fluidrachms 20 mils
Oil of Anise 48 minims. 5 mils
Deodorized Alcohol, sufficient to make 20 fluidounces 1000 mils
Mix them. Keep in completely filled, well-stoppered bot-
tles, in a cool, dark place.
40 THE CANADIAN FORMULARY
119. SYRUPUS ACACI/E
Syrup of Acacia
Mucilage of Acacia 1 fluidounce 25.0 mils
Simple Syrup 3 fluidounces 75.0 mils
Mix.
120. SYRUPUS CODElN>E PHOSPHATIS
Syrup of Codeine Phosphate
Codeine Phosphate 43 grains 5.00 Gm.
Alcohol (95%) 7 fluidrachms 47.50 mils
Distilled Water 3 fluidrachms 18.75 mils
Syrup, sufficient to make 20 fluidounces 1000 mils
Dissolve the codeine phosphate in the water and alcohol,
then add the syrup.
Note. — Recommended as being more stable than the official Syrup of
Codeine. The strength is identical with Syrupus Codeinae, P. B.
121. SYRUPUS EUCALYPTI COMPOSITUS
Compound Syrup of Eucalyptus
Fluid Extract of Eucalyptus 5 fluidounces 125.0 mils
Fluid Extract of Horehound 2 fluidounces 50.0 mils
Fluid Extract of Elecampane 2 fluidounces 50.0 mils
Fluid* Extract of Licorice 2 fluidounces 50.0 mils
Fluid Extract of Comfrey 2 fluidounces 50.0 mils
Ammonium Chloride 480 grains 28.0 Gm.
Magnesium Carbonate 240 grains 14.0 Gm.
Compound Spirit of Orange 4 fluidrachms 12.5 mils
Sugar 28 ounces 700.0 Gm.
Water, sufficient to make 40 fluidounces 1000 mils
Triturate the fluid extracts and compound spirit of orange
with the magnesium carbonate and 8 fluidounces (200 mils) of
water, and let stand two hours. Filter through a previously
moistened filter, passing enough water through the filter to
make 16 fluidounces (4(X) mils) of filtrate, in which dissolve the
sugar and ammonium chloride ; then add sufficient water to make
40 fluidounces (1000 mils).
122. SYRUPUS FERRI ET MANGANI lODIDI
Syrup of Iodide of Iron and Manganese
(N. F. 1906)
Iodine 3 oz. 172 grains 81.5 Gm.
Iron Wire, fine, bright, and finely cut 1% ounce 28.0 Gm.
Manganese Sulphate 1 oz. 48 grains 26.5 Gm.
Potassium Iodide 1 oz. 137 grains 31.5 Gm.
Diluted Alcohol (50%) 4 fluidounces 100.0 mils
Sugar 30 ounces 800.0 Gm.
Distilled Water, sufficient to make . . 40 fluidounces 1000 mils
THE CANADIAN FORMULARY 41
Mix the iron with 10 fluidounces (250 mils) of distilled
water in a flask, add the iodine, and prepare a solution of ferrous
iodide, in the usual manner, aiding the process, if necessary, by-
heating the contents of the flask, at first gently, and finally to
the boiling point. Filter the liquid through a small filter, direct-
ly upon the sugar contained in a suitable bottle. Dissolve the
manganese sulphate in 5 fluidounces (125 mils) of distilled water,
and the potassium iodide in 4 fluidounces (100 mils) of diluted
alcohol. Mix the two solutions .and filter into the same bottle
which contains the sugar and the iron solution. Wash the filter
with 10 fluidrachms (32 mils) of cold distilled water, receiving the
washings in the same bottle. Agitate until the sugar is dis-
solved, and if necessary, strain. Finally make up the volume
with distilled water to 40 fluidounces (or 1000 mils).
Note. — Each fluidrachm contains about 6 grains (0.4 Gm.) of ferrous
iodide and 3 grains 0.2 Gm.) of manganese iodide.
Average dose, 15 minims (1 mil).
123. SYRUPUS FERRI PHOSPHATIS COMPOSITUS
Compound Syrup of Phosphate of Iron
Compound Syrup of the Phosphates
"Parrish's Chemical Food."
(r;. F. 1906)
Precipitated Calcium Carbonate, 1 oz. 200 grains 35.0 Gm.
Soluble Ferric Phosphate 320 grains 17.5 Gm.
Ammonium Phosphate 320 grains 17.5 Gm.
Potassium Bicarbonate 75 grains 4.0 Gm.
Sodium Bicarbonate 75 grains 4.0 Gm.
Citric Acid 3>8 ounces 82.0 Gm.
Glycerin 15 fluidounces 375.0 mils
Concentrated Phosphoric Acid, B. P. 2 fluidounces 50.0 mils
Orange Flower Water 5 fluidounces 125.0 mils
Tincture of Cudbear 5 fluidrachms 16.0 mils
Sugar 16 ounces 400.0 Gm.
Water, sufficient to make 40 fluidounces 1000 mils
Triturate the precipitated calcium carbonate with the potas-
sium and sodium bicarbonates, citric acid, glycerin and
orange-flower water, and gradually add the cone, phosphoric acid,
stirring until solution has been effected. Dissolve the ferrie
phosphate and the ammonium phosphate in 10 fluidounces (250
mils) of hot water, cool and add the solution to that previously
prepared. Filter the whole through a pellet of absorbent cotton
42 THE CANADIAN FORMULARY
placed in the neck of a funnel, and receive the filtrate in a grad-
uated bottle containing the sugar. Agitate until the sugar is dis-
solved, then add the tincture of cudbear, and lastly, enough water
to make 40 fluidounces (1000 mils).
Note. — Each fluidrachm contains about 2 grains (0.13) Gm. of cal-
cium phosphate, 1 grain (0.065 Gm.) each of phosphates of iron and of
ammonium and smaller quantities of sodium and potassium phosphates.
Average dose, 1 fluidrachm (4 mils).
124. SYRUPUS GLYCYRHHIZ>E AROMATICUS
Aromatic Syrup of Licorice
Licorice Root, cut small 8 ounces 200.0 Gm.
Solution of Ammonia, B. P 1 fluidounce 25.0 mils
Oil of Coriander 20 minims. 1.0 mils
Oil of Cloves 10 minims. 0.5 mil
Alcohol (95% ) 2 fluidounces 50.0 mils
Granulated Sugar 27 ounces 675.0 Gm.
Water, sufficient to make 40 fluidounces 1000 mils
Macerate the licorice root with 16 fluidounces (400 mils) of
disglled water mixed with 160 minims. (8.5 mils) of solution of
ammonia, for twelve hours ; strain and express, reserving the
colature. Repeat this operation with the pressed marc and new
menstruum of ammonia and water twice, straining, pressing and
reserving the colature after each maceration. Mix the several
colatures and evaporate over a water-bath until the liquid is con-
centrated to 16 fluidounces (400 mils), then cool and filter. To
the filtrate add the oils, previously dissolved in the alcohol, and
dissolve the sugar, by percolation, in the mixed liquids, then add
enough water to make 40 fluidounces (1000 mils).
If preferred, the following formula may be substituted for
the foregoing :
Fluid Extract of Licorice (for Quinine
Mixtures) 8 fluidounces 200.0 mils
Oil of Coriander 20 minims. 1.0 mils
Oil of Cloves 10 minims. 0.5 mil
Alcohol (95%; 2 fluidounces 50.0 mils
Granulated Sugar 27 ounces 675.0 Gm.
Water, sufficient to make 40 fluidounces 1000 mils
Mix the fluid extract with the alcohol, in which the oils have
been previously dissolved, and 8 fluidounces (200 mils) of dis-
tilled water. Dissolve the sugar in this liquid and add enough
water to make 40 fluidounces (10(X) mils.).
THE CANADIAN FOKMTLAUY 43
125. SYRUPUS HYPOPHOSPHITUM COMPOSITUS
Corripound Syrup of Hypophosphites
Calcium Hypophosphite 2^ oz. 58 grains 29.5 Gm.
Sodium Hypophosphite 2}^ oz. 80 grains 36.5 Gm.
Potassium Hypophosphite ...... 1^4 oz. 94 grains . 18.3 Gm.
Manganese Hypophosphite 80 grains 2.3 Gm.
Quinine 40 grains 1.15 Gm.
Strychnine 10 grains 0.28 Gm.
Ferrous Sulphate, in crystals 120 grains 3.45 Gm.
Dilute Hypophosphorus Acid, a sufficient quantity.
Concentrated Phosphoric Acid, B. P. . .45 minims 1.15 mils
Granulated Sugar 65 ounces 813.0 Gm.
Distilled Water, sufficient to make . . 80 fluidounces 1000 mils
Dissolve the sodium and potassium hypophosphites and 960
grains (27.2 Gm.) of calcium hypophosphite in 35 fluidounces
(437.5 mils) of boiling distilled water. Dissolve the manganese
hypophosphite in 5 fluidounces (62.5 mils) of hot distilled water,
then dissolve the alkaloids in this solution, with the aid of a mini-
mum quantity of dilute hypophosphorus acid. Mix the two
solutions and filter, if necessary. Make a syrup by dissolving the
sugar in the filtrate by the cold percolation process. Dissolve
the ferrous sulphate in 6 fluidrachms (9.5 mils) of water, pre-
viously mixed with the concentrated phosphoric acid. Also dis-
solve 82 grains (2.3 Gm.) of calcium hypophosphite in 6 fluid-
rachms (9.5 mils) of water ; mix this solution with the ferrous
sulphate, solution, let the mixture stand for twelve hours and
filter out the precipitate. (The filtrate will contain approximate-
ly 80 grains (2.3 Gm.) of ferrous hypophosphite.) Mix the fil-
trate with the syrup and pass enough water through the contents
of the percolator to make the finished product measure 80 fluid-
ounces (1000 mils).
Note. — Each fluidounce of this syrup contains sodium hypophos-
phite, 16 grains; calcium hypophosphite, 12 grains; potassium hypophos-
phite, 8 grains; manganese and ferrous hypophosphites, 1 grain each;
quinine, Yz grain, and strychnine, % grain.
Dose, one to two fluidrachms (4 to 8 mils).
126. SYRUPUS PICIS LIQUID/E
Syrup of Tar
Tar 3 ounces 75 Gm.
White Sand 4 ounces 100 Gm.
Glycerin 4 fluidounces 100 mils
Sugar 32 ounces 800 Gm.
Water, sufficient to make 40 fluidounces 1000 mils
44 THE CANADIAN FORMULARY
Mix the tar intimately with the white sand, pour on 8 fluid-
ounces (200 mils) of Avater, and stir frequently for 12 hours, then
pour off the water and throw it away. Pour 16 fluidounces (400
mils) of boiling water upon the residue, stir well and frequently
for 15 minutes, add the glycerin and set aside for 24 hours, occa-
sionally stirring, and decant the clear solution and filter. Dis-
solve the sugar in the filtrate, with gentle heat, cool, strain and
pass enough water through the strainer to make 40 fluidounces
(1000 mils).
127. SYRUPUS PRUNI VIRGINIAN>E CUM OLEO MORRHU/E ET
MALTO
Syrup of Wild Cherry with Cod Liver Oil and Malt
Cod Liver Oil 10 fluidounces 250.0 mils
Extract of Malt 10 fludiounces 250.0 mils
Glycerin 2 fluidounces 50.0 mils
Powdered Acacia 2 ounces 50.0 Gm.
Oil of Peppermint 30 minims. 1.5 mils
Syrup of Wild Cherry, sufficient to
make 40 fluidounces 1000 mils
Triturate the oils with the powdered acacia until a homo-
geneous mixture results ; then add, all at once, 12 fluidounces
(300 mils) of syrup of wild cherry, and stir briskly with the
peslle, until the mixture is a perfect emulsion. Mix the extract
of malt, glycerin and 5 fluidounces (125 mils) of syrup of wild
cherry and add gradually under constant stirring to the emulsion;
finally, if necessary, sufficient syrup of wild cherry to make
40 fluidounces (1000 mils).
128. SYRUPUS QUININ>E PHOSPHO-MURIATIS
Compound Syrup of Phospho-Muriate of Quinine.
Potassium Bicarbonate 616 grains 35.0 Gm.
Magnesium Carbonate 352 grains 20.0 Gm.
Precipitated Calcium Carbonate 352 grains 20.0 Gm.
Quinine Hydrochloride 70 grains 4.0 Gm.
Strychnine Hydrochloride 2^4 grains 0.15 Gm.
Orange Flower Water, natural, con-
centrated 5 fluidounces 125.0 mils
Phosphoric Acid, 85% 5 fluidounces 125.0 mils
Soluble Ferric Phosphate 282 grains 16.0 Gm.
Water 310 minims. 16.0 mils
Syrup, sufficient to make 40 fluidounces 1000 mils
Dissolve the several carbonates and the alkaloidal salts in
the phosphoric acid, previously diluted with the orange flower
water. Then dissolve the soluble ferric phosphate in the water,
previously warmed, and add it to the foregoing solution, and last-
ly add sufficient syrup to make 40 fluidounces (1000 mils).
THE CANADIAN FORMULARY 45
129. SYRUPUS RUBI AROMATICUS
Aromatic Syrup of Blackberry.
(N. F. 1906)
Blackberry Root Bark 5 ounces 125.0 Gm.
Cinnamon Bark 262 grains 15.0 Gm.
Nutmeg 262 grains 15.0 Gm.
Cloves 140 grains 8.0 Gm.
Allspice 140 grains 8.0 Gm.
Granulated Sugar 26 ounces 650.0 Gm.
Alcohol (95%)
Water, Blackberry Juice (fresh), of
each sufficient to make 40 fluidounces 1000 mils
Reduce the blackberry root bark and the aromatics to a
moderately coarse (No. 40) powder and percolate in the usual
manner with a menstruum of equal volumes of alcohol and
water, until 10 fluidounces (250 mils) of percolate are obtained.
To this, add 18 fluidounces (450 mils) of blackberry juice, and
dissolve the sugar in the liquid by agitation. Lastly, add enough
blackberry juice to make 40 fluidounces (1000 mils).
130. SYRUPUS SARS/E COMPOSITUS
Compound Syrup of Sarsaparilla -
(U. S. P. 1905)
Fluid Extract of Sarsaparilla 8 fluidounces 200.0 mils
Fluid Extract of Licorice 5 fluidrachms 15.0 mils
Fluid Extract of Senna 5 fluidrachms 15.0 mils
Sugar 30 ounces 750.0 Gm.
Oil of Sassafras 2 minims. 0.2 mils
Oil of Anise 2 minims. 0.2 mils
Oil of Gaultheria 2 minims. 0.2 mils
Water, sufficient to make 40 fluidounces 1000 mils
Add the oils to the mixed fluid extracts, and shake the liq-
uid thoroughly, then add water enough to make up the volume
to 24 fluidounces (600 mils), and mix well. Set the mixture
aside for one hour, and then filter it. Dissolve the sugar in the
filtrate with the aid of a gentle heat. Cool, strain, and add
enough water through the strainer to make the finished product
measure 40 fluidounces (1000 mils).
131. SYRUF^US SENEG/C
Syrup of Senega
Fluid Extract of Senega 8 ounces 200.0 mils
Glycerin 2 ounces 50.0 mils
Sugar 40 ounces 1000.0 Gm.
Magnesium Carbonate 360 grains 20.0 Gm.
Distilled Water, sufficient to make . . 40 fluidounces 1000 mils
46 THE CANADIAN FORMULARY
Mix the fluid extract and glycerin, then triturate with the
magnesium carbonate and 4 ounces (100 Gm.) of sugar, then
gradually add 10 ounces (250 mils) of water and filter. Dissolve
the sugar in the remainder of the filtrate by the percolation meth-
od and add water, if necessary, to make 40 fluidounces (1(XX)
mils).
132. SYRUPUS SULPHATUM COMPOSITUS
Compound Syrup of Sulphates
Compound Syrup of Magnesium, Iron and Manganese Sulphates
Magnesium Sulphate 5 ounces 250.0 Gm.
Ferrous Sulphate 80 grains 9.2 Gm.
Manganese Sulphate 40 grains 4.6 Gm..
Dilute Sulphuric Acid 400 minims. 41.6 mils
Solution of Carmine, C. F 100 minims. 10.4 mils
Syrup of Lemon, sufficient to make . . 20 fluidounces 1000 mils
Powder the salts and dissolve them in the syrup of lemon, to
which the dilute sulphuric acid has previously been added ; finally
add the solution of carmine and filter, if necessary.
133. SYRUPUS THYMI COMPOSITUS
Compound Syrup of Thyme
(B. P. C.)
Liquid Extract of Garden Thyme ... 2 fluidounces 100.0 mils
Licmid Extract of Wild Thvme 2 fluidounces 100.0 mils
Alcohol (90%) .' 1 fluidounce 50.0 mils
Potassium Bromide 400 grains 44.5 Gm.
Simple Syrup 15 fluidounces 750.0 mils
Distilled Water, sufftcient to make . . 20 fluidounces 1000 mils
Dissolve the potassium bromide in 1 fluidounce (50 mils) of
distilled water. Mix the alcohol, liquid extracts and syrup, then
add the potassium bromide solution, and sufficient distilled water
to make 20 fluidounces (1000 mils).
Note. — Each fluidrachm contains 2% grains (0.163 Gm.^ of potas-
sium bromide.
134. SYRUPUS TRIFOLII COMPOSITUS
Compound Syrup of Trifolium
Compound Syrup of Red Clover Blossoms
Fluid Extract of Red Clover Pdossoms 20 fluidrachms 64.00 mils
Fluid Extract of Burdock 10 fluidrachm.s 32.00 mils
Fluid Exrtacts of Berberis Aquifolium 10 fluidrachms 32.00 mils
Fluid Extract of Stillingia 10 fluidrachms 32.00 mils
Fluid Extract of Poke Root 10 fluidrachms 32.00 mils
Fluid Extract of Cascara Amarga ... 10 fluidrachms 32.00 mils
Fluid Extract of Prickly Ash Bark . .2^ fluidrachms 8.00 mils
Potassium Iodide 320 grains 18.25 Gm.
Sugar 45 ounces 1 125.00 Gm.
Water, sufficient to make 40 fluidounces 1000 mils
THE CANADIAN FORMULARY 47
Mix the fluid extracts with 12j/^ fluidounces (312.5 mils)
of water ; let stand for a few hours, filter, and dissolve the sugar
and potassium iodide in the filtrate, and strain; then add suffi-
cient water to make 40 fluidounces (1000 mils).
135 SYRUPUS ZINGIBERIS
Syrup of Ginger
Solution of Ginger 1 volume
Simple Syrup 9 volumes
Mix.
Note. — This preparation is equivalent in strength to the official
syrup of ginger.
136. THYMOLIS lODIDUM
Thymol Iodide.
Dithymol Di-iodide
Potassium Iodide 124 grains 8.0 Gm.
Iodine, resublimed 93 grains 6.0 Gm.
Sodium Hydroxide 27>^ grains 1.8 Gm.
Thymol, in crystals 27 grains 1.7 Gm.
Distilled Water, a sufficient quantity.
Dissolve the iodine and potassium iodide in one fluidounce
(28.4 mils) of distilled water and add distilled water to make one
and a half fluidounces (42.6 mils). Dissolve the sodium hydrox-
ide in 1 fluidounce (28.4 mils) of distilled water, and in this solu-
tion dissolve the thymol, and dilute with water to make Ij^ fluid-
ounces (42.6 mils). Into this solution slowly pour the iodine
solution under constant stirring, and wash the resulting precipi-
tate, by alternate affusion and decantation with distilled water,
then drain and dry carefully.
137. TINCTURA AURANTM CORTICIS DULCIS RECENTIS
Tincture of Fresh Sweet-Orange Peel
Fresh Sweet-Orange Peel 5 ounces 250.0 Gm.
Rectified Spirit, sufficient to make ... .20 fluidounces 1000 mils
Prepare by the maceration process.
138. TINCTURA CARMINATIVA
Carminative Tincture
Spirit of Chloroform 5 fluidounces 250.0 mils
Compound Tincture of Cardamom ... 5 fluidounces 250.0 mils
Compound Tincture of Lavender .... 5 fluidounces 250.0 mils
Aromatic Spirit of Ammonia 5 fluidounces 250.0 mils
Mix.
Adult dose, 1 fluidrachm (4 mils).
48 THE CANADIAN FORMULARY
139. TINCTURA FERRI CITRO-CHLORIDI
Tincture of Citro-Chloride of Iron
Tasteless Tincture of Iron
Strong Solution Ferric Chloride, B.P. 5 fluidounces 125.0 mils
Citric Acid, in powder ... .6 ounces 200 grains 160.5 Gm.
Sodium Bicarbonate 7 ounces 300 grains 195.75 Gm.
Alcohol (95%) 3 fluidounces 75.0 mils
Distilled Water, sufficient to make . . 20 fluidounces 500.0 mils
Heat 7^ fluidounces ( 187.5 mils) of water to the boiling
point, and dissolve in it the citric acid, continuing the heat while
adding the sodium bicarbonate in portions, and stirring with a
glass rod, if necessary ; when efl:ervescence has ceased, add the
strong solution of ferric chloride and cool the mixture. Then
add the alcohol and sufficient distilled water to make 20 fluid-
ounces (500 mils).
Note. — This preparation is equivalent in quantity of iron (but not
in the quantity of alcohol) to Tinctura Ferri Perchloridi. P. B.
140. TINCTURA IGNATI/E ALKALINA
Alkaline Tincture of Ignatia
Gouttes Ameres de Baume
St. Ignatius' Bean 20 ounces 500.0 Gm.
Potassium Carbonate 90 grains 5.2 Gm.
Alcohol (60%), sufficient to make ... .40 fluidounces 1(X)0 mils
Macerate for ten days and filter.
Dose, 5 to 20 minims (0.3 to 1.2 mils).
141. TINCTURA lODI, CHURCHILL
Churchill's Tincture of Iodine
(N. F. 1906)
Iodine, resublimed 3 ounces 131 grains 165.0 Gm.
Potassium Iodide 289 grains 33.0 Gm.
Water 5 fluidounces 250.0 mils
Alcohol (95%©), sufficient to make ... 20 fluidounces 1000 mils
Dissolve the potassium iodide in the water, then add the
iodine, and lastly, enough alcohol to make the tincture, when
completed, measure 20 fluidounces (1000 mils).
142. TINCTURA lODI DECOLORATA
Decolorized Tincture of Iodine
Iodine, resublimed 250 grains 26.0 Gm.
Strong Solution of Ammonia, B. P. . . 10 fluidrachms 62.5 Gm.
Alcohol (95%), sufficient to make ...20 fluidounces 1000 mils
Dissol the iodine in the alcohol and add the strong solution
of ammonia. Keep the liquid in a warm place until decolorized,
then filter in a covered funnel, and burn the filter while still wet.
THE CANADIAN' FOKMULAUY 49
143. TINCTURA PERSIONIS
Tincture of Cudbear
(N. F. 1906)
Cudbear 5 ounces 125.0 Gm.
Alcohol (95%) and Water, of each,
sufficient to make 40 fluidounces 1000 mils
Prepare by maceration with a menstruum of alcohol, one vol-
ume, and water, two volumes, until 40 fluidounces (1000 mils)
are obtained.
Note. — This preparation is intended as a colouring agent when a
bright-red tint or colour is to be desired, particularly in acid liquids.
144. TINCTURA PERSIONIS COMPOSITA
Compound Tincture of Cudbear
(N. F. 1906)
Cudbear 300 grains 17.0 Gm.
Caramel 4 ounces 100.0 Gm.
Alcohol (95%) and Water, of each,
sufficient to make 40 fluidounces 1000 mils
Mix alcohol, one volume, with water, two volumes. Mace-
rate the cudbear with 30 fluidounces (750 mils) of the menstruum
during twenty-four hours, agitating occasionally ; filter through
paper and add the caramel, previously dissolved in 5 fluidounces
(125 mils) of water. Then pass sufficient of the before-mention-
ed menstruum through the filter to make the whole measure 40
fluidounces (1000 mils).
Note. — rhis preparation is intended as a colouring agent, when a
brownish-red tint or colour Is desired.
145. TINCTURA SAPONIS VIRIDIS
Tincture of Green Soap
Liniment of Soft Soap
Green Soap 12 ounces 600.0 Gm.
Oil of Lavender 200 minims. 20.0 mils
Alcohol (95%) 10 fluidounces 500.0 mils
Distilled Water, sufficient to make . . 20 fluidounces lOCXD mils
Mix the oil of lavender with the alcohol, add the green soap
and macerate for forty-eight hours, agitating occasionally. Then
filter, and pass enough water through the filter to make 20 fluid-
ounces (1000 mils).
146. TINCTURA TOLUTANA SOLUBILIS
Soluble Tincture of Tolu
(N. F. 1906)
Tolu Balsam 3^^ ounces 100.0 Gm.
iMagnesium Carbonate 200 grains 12.0 Gm.
Glycerin 16 fluidounces 400.0 mils
Water and Alcohol (95%), of each,
sufficient to make 40 fluidounces 1000 mils
50 THE CANADIAN FORMULARY
Mix 8 fluidounces (200 mils) of alcohol with the glycerin,
and dissolve the tolu balsam in the mixture, with the aid of heat,
avoiding loss by evaporation. Then add 15 fluidounces (375
mils) of water and allow the mixture to cool Pour ofif the milky
fluid from the resinous precipitate (which latter is to be reject-
ed), mix it with the magnesium carbonate by trituration, and fil-
ter. Lastly, pass enough of a mixture of alcohol, one volume,
and water, two volumes, through the filter, to make the whole fil-
trate measure 40 fluidounces (1000 mils).
147. ULGUENTUM ACIDi CARBOLIC! COMPOSITUM
Compound Ointment of Carbolic Acid
IMercuric Nitrate Ointment, B. P 4 ounces 40 Gm.
Sublimed Sulphur 1 ounce 10 Gm.
Phenol (crystals) 2 ounces 20 Gm.
Olive Oil 2 ounces 20 Gm.
Yellow Wax 2 ounces 20 Gm.
Dissolve the sulphur in the previously heated olive oil and
melt the wax in this solution with a gentle heat. Stir while cool-
ing, and when nearly cold, add the phenol, and stir until dis-
solved. Rub the mercuric nitrate ointment in a mortar until
smooth ; then incorporate with it the mixture previously pre-
pared.
* 148. UNGUENTUM CAPSICI COMPOSITUM
Compound Capsicum Ointment
Unguentum Calefaciens
Oleoresin Capsicum 2 fluidrachms 8.0 mils
Croton Oil 1 fluidrachm 4.0 mils
Camphor (in powder) 240 grains 16.0 Gm.
Oil of Turpentine 1 fluidounce 32.0 mils
Oil of Cajuput 4 fluidrachms 16.0 mils
Oil of Cloves 2 fluidrachms 8.0 mils
Oil of Wintergreen (Synthetic) 2 fluidrachms 8.0 mils
Beeswax (yellow) 1 ounce 32.0 Gm.
Soft Parafin (yellow) 16 ounces 500.0 Gm.
Melt the beeswax, add the soft paraffin, and continue the
heat, if necessary, until the latter liquifies ; then add the remain-
ing ingredients, which have been previously mixed together ; then
strain through muslin, and stir until it begins to congeal.
148a. UNGUENTUM CHRYSAROBINI COMPOSITUM
Druhe's Ointment
Chrysarobin 20 parts
Soft Soap 25 parts
Salicylic Acid 20 parts
Anhydrous Wool-Fat 25 parts
Oil of Birch Tar (Oleum Rusci) 10 parts
Mix in the above order.
THE CANADIAN FORMULARY 51
149. UNGUENTUM ICHTHYOLIS COMPOSITUM
Compound Ichthyol Ointment
Ichthyol 1 ounce 20.0 Gm.
Solution of Lime 4 fluidounces 80.0 mils
Anhydrous Wool-Fat 5 ounces 100.0 Gm.
Soft Paraffin 5 ounces 100.0 Gm.
Zinc Ointment 2}4 ounces 50.0 Gm.
Triturate the ichthyol with the lime water; add the wool fat
gradually, under constant trituration, and then the other ingredi-
ents in a similar manner.
150. UNGUENTUM lODI DENIGRESCENS
Stainless Iodine Ointment
Iodine 1 ounce 10.0 Gm.
Soft Paraffin 19 ounces 190.0 Gm.
Finely powder the iodine ; heat the paraffin until liquified,
then add the powdered iodine, continuing a gentle heat, and stir-
ring until fully combined, then remove from heat and stir un-
til it congeals.
151. UNGUENTUM EMPLASTRI PLUMBI
Ointment of Lead Plaster
Diachylon Ointment
Lead Plaster 1 ounce 110.0 Gm.
Soft Paraffin 1 ounce 110.0 Gm,
Oil of Bergamot 4 minims 1.0 mils
Melt the lead plaster and paraffin together; when the mix-
ture approaches the temperature of 160° to 170° F. (71° to 76° C.),
add the oil and stir until it congeals.
152. UNGUENTUM MENTHOLIS COMPOSITUM
Compound Menthol Ointment
Hydrated Chloral 160 grains 12.0 Gm.
Menthol 320 grains 24.0 Gm.
Oil of Gaultheria 320 grains 24.0 mils
Hydrous Wool-Fat 4 ounces 125.0 Gm.
Soft Paraffin (white, sufficient to make 16 ounces 500.0 Gm.
Dissolve the hydrated chloral and menthol in the oil. Melt
together, at a moderate heat, the hydrous wool-fat and soft par-
affin ; then add the above solution and stir until it congeals.
52 THE CANADIAN FORirULAKY
153. UNGUENTUM PHENOLIS CAMPHORATUM
Camphorated Phenol Ointment
Phenol (crystals) 15 parts
Camphor 30 parts
Hydrous Wool-Fat 60 parts
Yellow Beeswax 40 parts
YeJlow Soft Paraffin 300 parts
Liquefy the paraffin, beeswax and wool-fat, with the aid of
gentle heat, and while the mixture is still warm, dissolve in it the
phenol and camphor, and stir until it congeals.
154. UNGUENTUM RESORCINI COMPOSITUM
Compound Resorcin Ointment.
Soothing Ointment
Resorcin 6 parts
Zinc Oxide 6 parts
Bismuth Subnitrate 6 parts
Oil of Cade 12 parts
Yellow Beeswax 10 parts
Soft Paraffin (white) 25 parts
Anhydrous Wool-Fat 28 parts
Glycerin 13 parts
Dissolve the resorcin in the glycerin and incorporate the zinc
oxicie, bismuth subnitrate and oil of cade. Melt the yellow bees-
wax, soft paraffin and anhydrous wool-fat, add to the other mix-
ture, and stir until it congeals.
Note. — Darkens on exposure to air and light, and should be kept in
air-tight containers.
155. UNGUENTUM SULPHURIS COMPOSITUM
Compound Sulphur Ointment
Wilkinson's Ointment — Hebra's Itch Ointment
Precipitated Calcium Carbonate 1 ounce 10.0 Gm.
Sublimed Sulphur X]/^ ounce 15.0 Gm.
Oil of Cade I]/, ounce 15.0 Gm.
Soft Soap 3 ounces 30.0 Gm.
Lard 3 ounces 30.0 Gm.
Mix the lard with the soft soap and oil of cade. Then grad-
ually incorporate the sublimed sulphur and precipitated calcitim
carbonate.
156. UNGUENTUM SULPHURIS ET RUSCI COMPOSITUM
Compound Ointment of Sulphur and Birch Tar
Sublimed Sulphur, sifted 32 parts
Potassium Carbonate 2 parts
Oil of Birch Tar, Russian (Oleum Rusci) . 2 parts
Zinc Ointment 16 parts
Benzoated Lard 32 parts
]\Iix intimately by trituration, in order to produce a smooth
and homogeneous ointment.
THE CANADIAN FORMULARY 53
157. UNGUENTUM SULPHURIS CINEREI COMPOSITUM
Compound Grey-Sulphur Ointment
(Edinburgh)
•Grey Sulphur (Sulphur Vivuin) 8 ounces 227.0 Gm.
Potassium Nitrate 60 grains 4.0 Gm.
Powdered White Hellebore 1 ounce 28.4 Gm.
Green Soap 3 ounces • 85.0 Gm.
Phenol (crystals) 120 grains 8.0 Gm,
Oil of Bergamot 30 minims. 2.0 mils
Olive Oil 30 minims. 2.0 mils
Lard 24 ounces 682.0 Gm.
\\'ater, a sufficient quantity.
Mix the lard and soap, and incorporate the grey sulphur and
powdered hellebore with the mixture. Add the potassium ni-
trate (previously dissolved in a little water), then the phenol (dis-
solved in the oil of bergamot and olive oil) and mix the whole
thoroughly.
158. UNGUENTUM ZINCI CARBONATIS COMPOSITUM
Compound Ointment of Zinc Carbonate
Zinc Carbonate 800 grains 45.0 Gm.
Salicvlic Acid 100 grains 5.5 Gm.
Hydrous Wool-Fat 800 grains 45.0 Gm.
Soft Paraffin (white) 5 ounces 125.0 Gm.
Benzoated Lard, sufficient to make ... 10 ounces 250.0 Gm.
Melt the soft paraffin with a gentle heat, remove from heat,
and dust into it the zinc carbonate and salicylic acid (previously
well powdered) ; stir until well mixed, then gradually add the
hydrous wool-fat and benzoated lard, and stir until cool.
159. UNGUENTUM ZINCI STEARATIS
Ointment of Zinc Stearate
Zinc Stearate, in tine powder 1 ounce 50.0 Gm.
White Paraffin Ointment 1 ounce 50.0 Gm.
Liquefy the paraffin ointment with the heat of a water bath ;
:add the zinc stearate. continuing the heat until the mixture be-
comes smooth, then stir while cooling, until it congeals.
160. VINUM COC>C
Wine of Coca
(U. S. P. 1905)
Fluid Extract of Coca 234 fluidounces 65.0 mils
Alcohol (95%) 3 fluidounces 75.0 mils
Sugar 3 ounces 75.0 Gm.
Red Wine, sufficient to make 40 fluidounces 1000 mils
Dissolve the sugar in 20 fluidounces (500 mils) of the wine,
add the alcohol and fluid extract of coca, and enough wine to
make the liquid measure 40 fluidounces (1000 mils). Set the
mixture aside for two days, then filter.
Dose, 4 fluidrachms (16 mils).
54 THE CANADIAN FORMULARY
161. VINUM PEPSINI
Wine of Pepsin
Pepsin 320 grains 36.5 Gm.
Hydrochloric Acid 2 fluidrachms 12.5 mils
Glycerin 2 flnidounces 50.0 mils
Sherry, sufficient to make 20 fluidounces 1000 mils
Dissolve the pepsin in the liquids, previously mixed.
162. VINUM OLEI MORRHUOLIS
Wine of Morrhuol
Morrhuol (Gaduol) 80 grains 8.5 Gm.
Fluid Extract of Glycyrrhiza 3 fluidounces 75.0 mils
Glycerin 2 fluidounces 50.0 mils.
Syrup of Wild Cherry 4 fluidounces 100.0 mils
Liquid Extract of Malt 8 fluidounces 200.0 mils
Compound Syrup of Hypophosphites. 4 fluidounces 100.0 mils
Fuller's Earth, in powder 240 grains 18.0 Gm.
Sherry Wine, sufficient to make 40 fluidounces 1000 mils
Mix the morrhuol with the glycerin and triturate with the
Fuller's earth ; add the fluid extracts and syrup of wild cherry ;
allow it to stand for 24 hours, agitating occasionally, then filter
and add the syrup of hypophosphites ; lastly, add sufficient sherry
wine to make 40 fluidounces (1000 mils).
163. VINUM OLEI MORRHUOLIS CUM FERRO ET CREOSOTQ
AROMATICUM
Aromatic Wine of Morrhuol with Iron and Creosote
Morrhuol 80 grains 8.5 Gm..
Fluid Extract of Glycyrrhiza 10 fluidrachms 62.5 mils
Glycerin 15 fluidrachms 95.0 mils
Tincture of Citro-Chloride of Iron . . .320 minims. 33.5 mils
Creosote 80 minims. 8.2 mils
Syrup of Wild Cherry 5 fluidounces 250.0 mils
Talc ' 1 ounce 50.0 Gm.
Sherry Wine (Canadian), sufficient to
make 20 fluidounces 1000 mils
Mix the morrhuol with the creosote, and rub in a mortar, with
the talc. Add the glycerin, with trituration, then the remain-
der of the ingredients, which have been previously mixed togeth-
er. Let the mixture stand for 48 hours ; then filter through paper,.
adding sherry wine sufficient to make 20 fluidounces (1000 mils)..
IN DEX
A Page
Acetic Turpentine Liniment. 35
Acidum Hypophosphorosum. 3
Adjuvant Elixir 6
Alcohol Deodoratum 3
Alkaline Antiseptic Solution. 27
Lithia Salt 38
Tincture of Ignatia . . .48
Allspice Water 4
Anisated Spirit of Ammonia. 39
Aniseed Cordial 6
Water 4
Anti-Asthmatic Elixir 9
Antiseptic Powder, Soluble. 34
Soap, Solution of 32
Solution 27
Aqua Olei Anethi 4
Anisi 4
Carui 4
Cinnamomi 4
Foeniculi 4
Menthae Piperitse 4
Menthje Viridis 4
Pimentae 4
Rosae 3
Artificial Carlsbad Salt 38
Aromatic Castor Oil 34
Elixir 7
Fluid Extract of Cascara 21
Syrup of Licorice 42
Syrup of Blackberry. . .45
Wine of Morrhuol with
Iron and Creosote. . 54
Calamine Lotion 33
Camphorated Chloral 5
Chloroform 5
Phenol Ointment 52
Capsulse Apiol et Argotini . 4
Colchicinae et Methyl
Salicylatis 4
Page
Capsules of Apiol and Ergotin 4
Colchicine and Methyl
Salicylates 4
Carlsbad Salt, Artificial 38
Carminative Tincture 47
Caraway Water 4
Cataplasma Kaolini 4
Ceratum Paraffin 5
Chemical Food, Parrish's. . .41
Churchill's Tinct. of Iodine. 48
Chloral Camphoratum 5
Chlorine Gargle 23
Chloroformum Camphoratum 5
Cinnamon Water 4
Cold Cream 5
Collodium Belladonnae 5
lodoformatum 6
Compound Acacia Powder .35
Benzoate Powder 36
Digestive Elixir 14
Elixir of Acetanilide 6
Buchu and Hyoscyamus 8
Cramp Bark 18
Digitalin 9
Euphorbia 9
Glycerophosphates . ... 12
with Quin. & Strych..l2
Pepsin 14
with Bismuth 14
with Quinine, Iron
and Strychnine 15
Quinine 9
Saw Palmetto 16
Sodium Salicylate 17
Essence of Vanillin 21
Glycerin of Heroin 24
Iodine Paint 35
Liniment of Methyl Sali-
cylate 26
Liniment of Betul 26
Liquid Paraffin ........ .34
Menthol Liniment 26
55
56
INDEX
Page
Compound Menthol Spray. .34
Milk Powder 36
Powder of Acetanilide .35
Pepsin 37
Santonin 37
Compound Ointment of
Capsicum 50
Carbolic Acid 50
Grey Sulphur 53
Ichthvol 51
Menthol 51
Resorcin 52
Sulphur & Birch Tar. 52
Zinc Carbonate 53
Solution of Borax 28
Bromo Chloral 28
Hypophosphites
without sugar ....30
Sandal Oil 32
Spirit of Asparagus ...39
Orange 39
•Sulphur Lotion 33
Syrup of
Eucalyptus 40
Hypophosphites 43
Magnesium, Iron and
" Manganese Sulphates.46
Phosphate of Iron . . .41
Red Clover Blossoms. 46
Sarsaparilla 45
Sulphates 46
Thyme 46
Trifolium 46
Tincture of Cudbear . . .49
Vanillin 21
Concentrated Infusion of
Buchu 25
D
Decolorized Tincture Iodine.48
Deodorized Alcohol 3
Diachylon Ointment 51
Digestive Powder 37
Dill Water 4
Dilute Solution of Iodine . .31
Page
Di-thymol Di-iodide 47
Dobell's Solution 28
Druhe's Ointment 50
Elixir Acetanilidi Composi-
tum 6
Adjuvans 6
Ammonii Bromidi 6
Anisi 7
Aromaticum 7
Aurantii 7
• Buchu et Hyoscyami Co. 8
Calcii et Sodii Glycero-
phosphatis 8
Calisay?e et Phosphatum 9
Calisayse Phosphaticum 9
Cinchonse 9
Cinchonse et Ferri 10
DigestivumCompositum.l4
Digitalini Compositum . 10
Euphorbise Compositum. 10
Ferri Pyrophos. cum
Quin. et Strych 11
Formini 11
Glycerophos. Co 12
Glycerophos. with Qui-
nine and Strychnine. 12
Glycyrrhizge 12
Dithii et Hydrangeae ... 13
Lithii Salicylatis 13
Papaini 13
Pepsini Compositum ..14
cum Bismutho 14
cum Quinina, Ferro
et Strychnina 15
et Bismuthi 15
Bismuthi et Strychninae.l6
Potassii Bromidi 16
Quinque Bromidorum.. 8
Rhei et Magnes.Acetatis 16
>erenoae Compositum. .16
Sex lodorum 17
Sodii Salicylatis Comp..l7
Terpini Hydratis et
Heroine 18
INDEX
Page I
57
Page
Elixir Terpini Hydratis
et Heroinse 18
Viburni Compositum ..18
Calisayse 9
Calisayae Phosphaticum. 9
Calisaya and Phosphates 9
Cinchona 9
Cinchona from Alkaloids 9
Digestive Ferments ... 14
Five Bromides 8
Formin 11
Glycerophos with Quin.
and Strych 12
. Glycerophosphate of Cal-
cium and Sodium.. 12
Hexamethyl tetramine. .11
Iron Pyrophos. with
Quinine and Strych. 11
Lactated Pepsin 14
Lactated Pepsin with
Bismuth 14
Lactated Pepsin with
Quinine, Iron and
Strychnine 15
Licorice 12
Lithium and Hydrangea. 13
Lithium Salicylate .... 13
Orange 7
Papain 13
Pepsin and Bismuth ...15
and Strychnine .... 16
Potassium Bromide ... 16
Rhubarb and Magnesium
Acetate 16
Six Iodides 17
Terpin Hydrate and
Codeine 17
Elixir Terpin Hydrate and
Heroine 18
Emulsio Iodoform 18
Olei Morrhuse 18
Olei Morrhuse cum Ferri
Phosphato 19
Olei Morrhuse cum Pep-
sino 19
Emulsion Cod Liver Oil 18
Emulsion Cod Liver Oil
with Pepsin 19
Cod Liver Oil with
Phosphate of Iron... 19
Iodoform 18
Essentia Limonis 20
Pepsini 20
Pepsini Phenolata . . . .20
Vanillini Composita . . .21
Essence of Lemon 20
Pepsin 20
Pepsin, Phenolated ....20
Ratafia 39
Extractum Buchu Fluidum.21
Cascarse Sagradae Aro-
maticum Fluidum ...21
Senegge Fluidum 22
Serpylli Liquidum 22
Thy mi Liquidum 22
Fennel Water 4
Ferrated Elixir of Cinchona. 10
Flavours for Emulsions ... .38
Fluid Extract of Buchu 21
Fluid Extract of Senega ... .22
Fermented Milk 25
Fuller's Lotion 33
Gargarisma Chlori 23
Gargle, Chlorine 22
Glycerinum Belladonnse ... .23
Bismuthi 23
Ferri lodidi 23
Ferri Phosphatis cum
Quinina et Strychnina.24
Heroini Compositum . .24
Heroini Compositum. . .24
lodi 24
Glycerin of Belladonna ... .23
Bismuth 23
Ferrous Iodide 23
Iodine
.24
58
INDEX
Page
Page
Glycerin Iron Phosphate,
Quinine and Strych-
nine 24
Triple Phosphates 24
Gouttes Ameres de Baume . . 48
H
Hebra's Itch Ointment ....52
Hiera Picra 36
Humanized !Milk 25
Humanizing ]Milk Powder . .36
Hypophosphorus Acid .... 3
Infusum Buchu Concentra-
tum 25
Iodine and Starch Paste ...35
Iodoform Collodium 6
Itch Ointment (Hebra's) ..52
Kumyss 25
Kaolin, Cataplasm of 4
Lac Fermentatum 25
Lac Humanisatum 25
Linimentum Album 25
Ammonii lodidi 26
Betulse Compositum . . .26
Mentholis 26
Mentholis Compositum. 26
Methylis Compositum. .26
Liniment of Amnion. Iodide. 26
Liquid Ext. Garden Thyme. 22
Wild Thyme 22
Liquid Green Soap 49
Liquor Amm. Valerianatis. .26
Antisepticus 27
Antisepticus Alkalinus .27
Auri et Arsenii Bromidi.28
Boracis Compositus . . .28
Bromo-Chloral Compos. 28
Carmini 29
Liquor Creosoti et lodi . . .29
Cresolis 29
Glusidi 30
Hypophosphitum Com-
positum sine Saccharo 30
lodi Dilutus 31
Opii Sedativus 31
Pectoralis 31
Potassii Citratis 31
Saponis Antisepticus . . .32
Olei Santali Flavi Co. . 32
Sodii Hydroxidi 32
Zingiberis 32
Lotio Calaminae 33
Calcis Sulphuratse 33
Opii Compositum ......33
Sulphuris Composita . .33
M
Magma ]\Iagnesia 34
Mandl's Solution 35
Menthol Liniment 34
Menthol, Compound Spray .34
Milk of Magnesia 34
Mixture, Butyl-Chloral 34
Mixture, Skeenes' 36
O
Oleum Ricini Aromaticum. .34
Ointment, Druhe's 50
Lead Plaster 51
Zinc Stearate 53
Paraffin Cerate 5
Parrish's Chemical Food . . .44
Pasta lodi et Amyli 35
Pectoral Solution 31
Peppermint Water 4
Pepsinum Saccharatum ... .35
Peptonizing Powder 37
Phenolated Essence Pepsin. 20
Phosphatic Emulsion 19
Pigmentum lodi Comp 35
Powder for Chalk Mixture. .37
INDEX
Page
Powder, Aloes and Canella. .30
Pulvis Acaciae Compositus. .35
Acetanilidi Compositus. 34
Aloes et Canellae 36
Antisepticus Solubilis . .36
Benzoatis Compositus. .36
Digestivus 37
Lactis Compositus 36
Pancreaticus Compos... 37
Pepsini Compositus. .. .37
Pro Mistura Creta Zl
Santonini Compositus. .37
R
Rose Water 3
Saccharated Pepsin 35
Sal Carolinum Factitium . . .38
Lithia Alkalinus 38
Sapores Pro Emulsionibus. .38
Sedative Liquid 31
Sedative Solution of Opium. 31
Simple Elixir 7
Skeenes' Mixture 36
Soluble Antiseptic Powder .36
Essence of Ginger 32
Tincture of Tolu 49
Solution of Ammonium Val-
erianate 26
Bromide of Gold and
Arsenic 28
Carmine 29
Cresol 29
Creosote and Iodine . . .29
Ginger 32
Gluside 30
Iodine (dilute) 31
Potassium Citrate 31
Saccharin 30
Soda 32
Sodium Hydroxide ....32
Mandl's 35
Vleminck's 33
59
Page
Soothing Ointment ....... .52
Spearmint Water 4
Spiritus Asparagi Comp. . . ,30
Ammonite Anisatus ...30
Amygdalae Amarae 39
Aurantii 39
Aurantii Compositus . .39
Spirit of Bitter Almond ... .39
Orange 39
Spray, Menthol Compound. 34
Stainless Iodine Ointment. .51
Stokes' Liniment 25
Sulphurated Lime Lotion . .33
Sweet Castor Oil 34
Syrupus Acaciae 40
Codeinae Phosphatis . . .40
Eucalypti Compositus. .40
Ferri et Mangani Iodidi.40
Ferri Phosphatis Com-
positus 41
Glycyrrhizae Aromat. . . .42
Hypophosphitum Com-
positus 43
Picis Liquidae 43
Pruni Virginianae cum
Oleo Morrhuae et Malto 44
Quininae Phospho-Muri-
atis 44
Rubi Aromaticus 45
Sarsae Compositus 45
Senegae 45
Sulphatum Compositus. 46
Thymi Compositus ... .46
Trifolii Compositus ... .46
Zingiberis 47
Syrup of Acacia 40
Codeine Phosphate ... .40
Iodide of Iron and Man-
ganese 40
Tar 43
Phospho-M u r i a t e of
Quinine 44
Senega 45
Ginger 47
Wild Cherry with Cod
Liver Oil and Malt. . .44
60
INDEX
Page
T
Tasteless Tincture of Iron. .47
Thymolis lodidum 47
Thymol Iodide _. . .47
Tinctura Aurantii Corticis
Dulcis Recentis 47
Carminativa 47
Ferri Citro-Chloridi . . .48
Ignatise Alkalina 48
lodi (Churchill) 48
lodi Decolorata 48
Persionis 49
Persionis Composita . . .49
Saponis Viridis 49
Tolutana Solubilis 49
Tincture Citro-Chloride of
Iron 48
Cudbear 49
Fresh Sweet-Orange
Peel 47
Green Soap 49
U
Unguentum
Acidi Carbolici Comp...50
Capsici Compositum . . .50
Calefaciens 50
Ungentum Chrysarobini
Compositum 50
Page
Unguentum Ichthyolis Com. 51
lodi Denigrescens 51
Mentholis Compositum. 51
Emplastri Plumbi 51
Phenolis Camphoratum.52
Resorcini Compositum .52
Sulphuris Compositum .52
Sulphuris et Rusci Com-
positum 52
Sulphuris Cinerei Com-
positum 53
Zinci Carbonatis Com-
positum 53
Zinci Stearatis 53
V
Vleminck's Solution 33
Vinum Cocse 53
Pepsini 54
Morrhuolis 54
Morrhuolis cum Ferro et
Creosoto Aromaticum.54
W
White Liniment 25
Wilkinson's Ointment 52
Wine of Coca 53
Pepsin 54
Morrhuol 54
^^ The Canadian formulary of
-^31 unofficial preparations
.23
G36
1921